Publication Date:
2021-05-19
Description:
Marine organisms represent a new source for the discovery of anti-inflammatory agents
(Grace et al., 1994), mainly obtained starting from sponges, coelenterates and algae. A
representative compound from algae, due to its great number of properties, is the epitaondiol
that inhibits the phospholipase A2 and the formation and/or release of prostaglandins and
leukotrienes. Taking into account these antecedents, we decided to evaluate extracts from
four Rhodophyte algae species of the genera Laurencia, Acantophora and Gracilaria in the
models of mouse ear oedema induced by croton oil, writhing induced by acetic acid in
mouse, and the assay of the tiobarbituric acid (TBA). The objective was to detect antiinflammatory,
analgesic and antioxidant properties of the extracts. The extract from the algae
of the genus Acantophora inhibits the mouse ear oedema induced by croton oil in 58%, and
the extracts from the genera Laurencia and Gracilaria inhibit the writhing induced by acetic
acid with values higher than 50%. None of the studied extracts had any effect in the assay of
the TBA. Therefore, it can be concluded that the studied algae extracts seem to have antiinflammatory
and analgesic properties, probably inhibiting the formation and/or release of
prostaglandins.
Description:
Published
Description:
anti-inflammatory, analgesic,
Keywords:
Algae
;
Antioxidants
;
Algae
;
Antioxidants
Repository Name:
AquaDocs
Type:
Journal Contribution
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