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  • herbal preparation  (2)
  • Alcohol hangover  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Alcohol hangover and Liv.52 (1991)
    Springer
    European journal of clinical pharmacology 40 (1991), S. 187-188 
    Details
    ISSN: 1432-1041
    Keywords: Alcohol hangover ; Liv.52 ; herbal preparation ; alcohol levels ; aldehyde levels ; social drinkers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Ethanol and acetaldehyde levels in blood and urine have been evaluated in 9 volunteers following administration of Liv.52 and placebo on the evening of the study and on the following morning. On the following morning the volunteers scored their symptoms and completed visual analogue scales. Single dose and multiple dose studies were done. Liv.52 produced a considerable reduction in blood and urine levels of ethanol and acetaldehyde after 12 h. It is possible that Liv.52 prevents the binding of acetaldehyde, bringing about higher initial blood levels followed by rapid elimination. It reduced the hangover symptoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00280075
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of Liv.52, a herbal preparation, on absorption and metabolism of ethanol in humans (1991)
    Springer
    European journal of clinical pharmacology 40 (1991), S. 189-191 
    Details
    ISSN: 1432-1041
    Keywords: Liv.52 ; hepatoprotection ; alcohol ; social drinkers ; herbal preparation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In 8 social drinkers, the effect of a single dose of Liv.52 or placebo on ethanol absorption has been studied after ingestion of 30 ml whisky in 5 min. The t1/2 absorption with Liv.52 was 3.62 min, significantly less than after placebo, 6.29 min. The peak concentration after Liv.52 (49.9 mg · 100 ml−1) was significantly higher than with placebo (40.5 mg · 100 ml−1). Whisky 120 ml consumed by regular alcohol users in 1 h, before and following 15 days of Liv.52 treatment produced significantly higher ethanol levels at 2, 3 and 4 h and significantly lower acetaldehyde levels at 3 and 4 h after Liv.52 treatment. Liv.52 enhanced the rate of absorption of ethanol and rapidly reduced acetaldehyde levels, which may explain its hepatoprotective effect on ethanol-induced liver damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00280076
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    Paper (German National Licenses)
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