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  • Life and Medical Sciences  (29)
  • Analytical Chemistry and Spectroscopy  (10)
  • Air temperature at 2 m height; BARO; Barometer; Baseline Surface Radiation Network; BSRN; DATE/TIME; Diffuse radiation; Diffuse radiation, maximum; Diffuse radiation, minimum; Diffuse radiation, standard deviation; Direct radiation; Direct radiation, maximum; Direct radiation, minimum; Direct radiation, standard deviation; HEIGHT above ground; Humidity, relative; HYGRO; Hygrometer; Japan; Long-wave downward radiation; Long-wave downward radiation, maximum; Long-wave downward radiation, minimum; Long-wave downward radiation, standard deviation; Long-wave upward radiation; Long-wave upward radiation, maximum; Long-wave upward radiation, minimum; Long-wave upward radiation, standard deviation; Monitoring station; MONS; Pyranometer, Kipp & Zonen, CM21, SN 960330, WRMC No. 16013; Pyranometer, Kipp & Zonen, CM21, SN 960331, WRMC No. 16014; Pyranometer, Kipp & Zonen, CM21, SN 960332, WRMC No. 16015; Pyrgeometer, Eppley, PIR, SN 29460F3, WRMC No. 16009; Pyrgeometer, Eppley, PIR, SN 30700F3, WRMC No. 16010; Pyrheliometer, Kipp & Zonen, CH1, SN 950093, WRMC No. 16011; Short-wave downward (GLOBAL) radiation; Short-wave downward (GLOBAL) radiation, maximum; Short-wave downward (GLOBAL) radiation, minimum; Short-wave downward (GLOBAL) radiation, standard deviation; Short-wave upward (REFLEX) radiation; Short-wave upward (REFLEX) radiation, maximum; Short-wave upward (REFLEX) radiation, minimum; Short-wave upward (REFLEX) radiation, standard deviation; Station pressure; TAT; Tateno; Thermometer  (7)
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  • 11
    Electronic Resource
    Electronic Resource
    Production of a colony-stimulating factor following differentiation of leukemic myeloblasts to macrophages (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 102 (1980), S. 323-331 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Leukemic cells in the myeloblastic stage from a murine myeloid leukemia cell line (M1) were induced to differentiate to macrophages by lipopolysaccharide (LPS) from Gram-negative bacteria. A granulocyte-macrophage colony-stimulating factor (CSF) was produced only during differentiation. After induction of differentiation, the continued presence of LPS was necessary to stimulate the macrophages to release CSF.In contrast, a macrophage cell line (Mm-1) derived from the M1 line produced CSF without LPS-stimulation, but CSF release was stimulated by the presence of LPS.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041020307
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  • 12
    Electronic Resource
    Electronic Resource
    Transport of nutrients by a thermophilic bacterium - reconstitution of vesicles from crystalline ATPase or solubilized alanine carrier (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 89 (1976), S. 569-573 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A strain of aerobic thermophilic bacteria was selected in order to purify highly stable membrane proteins and to reconstitute proteoliposomes capable of transporting nutrients from them. These proteins responsible for the transport could be divided into (1) proteins which supply energy to the transporting system, and (2) specific nutrient carriers driven by the energy. The former included a stable ATPase (TF1) and a lipoprotein (TF0) which rendered TF1 sensitive to energy transfer inhibitors. The complex of TF0 and TF1 could transport protons into reconstituted proteoliposomes upon hydrolysis of ATP. And one of the latter reported in this paper was alanine carrier protein which was driven by proton movement.TF1 was the first crystallized ATPase in biomembranes, and was reconstituted from its five different polypeptides, two of which were necessary for ATPase activity and four of which, for proton translocation. Purification of alanine carrier and reconstitution of proteoliposomes capable of alanine accumulation were also demonstrated.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040890413
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  • 13
    Electronic Resource
    Electronic Resource
    Differentiation and production of colony-stimulating factor induced by immunostimulants in a leukemia cell line (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 105 (1980), S. 33-38 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Immunostimulants from various microorganisms were tested on a myeloid leukemia cell line (Ml) for the ability to induce production of CSF and to cause differentiation of these cells. Based on their activities, the compounds were divided into two general classes: those inducing extensive cellular differentiation and those devoid of this effect. The stimulants which were active in this regard always produced large quantities of CSF, whereas those devoid of a differentiating effect did not cause CSF production. Even the potent stimulants had no effect on the D- subline, in which the differentiation was not inducible.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041050106
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  • 14
    Electronic Resource
    Electronic Resource
    Production of the inducer for macrophage and granulocyte colonies by leukemic cells (1968)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 72 (1968), S. 251-253 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cell lines from a myeloid, an erythroid, and two lymphoid leukemias, were tested for the production of the inducer required for the formation of macrophage and granulocyte colonies. It was shown that the inducer was produced by all lines except one of the lymphoid leukemias.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040720313
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  • 15
    Electronic Resource
    Electronic Resource
    The stimulation of tumor cell growth by a substance produced by normal and tumor cells (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 73 (1969), S. 43-47 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: It has been shown that a dialyzable substance produced by normal and tumor cells can stimulate the growth of a myeloid, erythroid, and two lymphoid leukemias, and a sarcoma. The growth stimulation of the tumor cells was observed as an increase in cloning efficiency and number of cells per colony. Rat granulocytes stimulated the growth of mouse tumor cells as efficiently as a variety of mouse cells. The stimulating substance was found in conditioned medium, and it was produced by all the normal and tumor cells tested.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040730107
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  • 16
    Electronic Resource
    Electronic Resource
    Reversible effects of dibutyryl cAMP on laminin and type IV collagen secretion from retinoic acid treated F9 cells (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 125 (1985), S. 263-272 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effects of dibutyryl cAMP on the differentiation of embryonal carcinoma F9 cells were studied mainly using the secretion of laminin and type IV collagen as the marker. For this purpose, F9 cells were labeled with 35Smethionine and radioactive proteins in the medium were analyzed by SDS-polyacrylamide gel electrophoresis. Treatment of F9 cells with retinoic acid alone induced differentiation into cells secreting type IV collagen. The combination of retinoic acid and dibutyryl cAMP stimulated laminin secretion in addition to type IV collagen secretion. This effect of dibutyryl cAMP was observed only 16 h after adding dibutyryl cAMP. Immunofluorescence staining demonstrated that the majority of the cells in culture were converted into cells secreting laminin under these conditions. In contrast to the irreversible effect of retinoic acid, the effect of dibutyryl cAMP on laminin and type IV collagen secretion was reversible at least during the first 5 days of maintaining cells in the medium containing retinoic acid plus dibutyryl cAMP. Removal of dibutyryl cAMP from the culture medium decreased the protein secretion to the basal levels within 2 days. This reversibility was not due to a change in cell number. An in vitro translation assay also suggested the reversible effect of dibutyryl cAMP on the levels of laminin mRNA. Coinciding with variations of the protein secretion, a reversible and homogeneous change in the morphology of retinoic acid generated F9 cells was observed by dibutyryl cAMP.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041250214
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  • 17
    Electronic Resource
    Electronic Resource
    Further studies on the differentiation of a cell line of myeloid leukemia (1970)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 76 (1970), S. 175-184 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A limited time of contact with a conditioned medium from embryo cells induced phagocytotic activity in a cell line of myeloid leukemia followed by the loss of colony forming and leukemogenic capacity. After two days in a high concentration of the conditioned medium, the colonies showed morphological changes which indicated the differentiation of this line of cells. The differentiation-stimulating factor present in the conditioned medium was relatively thermolabile, while the growth-stimulating factor was highly thermostable. Both factors could pass through a dialysis membrane.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040760207
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  • 18
    Electronic Resource
    Electronic Resource
    The polyprotein nature of substance P precursors (1989)
    New York, NY : Wiley-Blackwell
    BioEssays 10 (1989), S. 62-69 
    Details
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Substance P and related tachykinin peptides probably act as neurotransmitters or modulators of neurotransmission, and regulate biological processes as diverse as salivary secretion and transmission of pain signals. Substance P peptide sequences are expressed in three distinct mRNAs that are generated from one gene by differential RNA splicing. In addition to substance P, as many as three other tachykinin peptides can be generated from the polyprotein precursors by differential posttranslational processing. Three tachykinin receptor subtypes have been extensively characterized which differentially interact with the naturally occurring tachykinin peptides. Therefore, the generation of diversity of tachykinin peptides results from differential precursor RNA splicing and differential posttranslational processing. The specificity of peptide responses is the result of selective receptor subtype expression.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bies.950100207
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  • 19
    Electronic Resource
    Electronic Resource
    Epithelial shape change in mouse embryonic submandibular gland: Modulation by extracellular matrix components (1989)
    New York, NY : Wiley-Blackwell
    BioEssays 11 (1989), S. 163-167 
    Details
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Early morphogenesis of mouse submandibular gland provides an excellent model for the formation of epithelial lobules as a consequence of epithelial-mesenchymal interactions. Both proteoglycans and a glycosaminoglycan, high molecular weight components which contain amino-sugars and hexuronic acids, seem to be important in maintaining the lobular structure through the formation of epithelial basal lamina. Collagen also appears to play a crucial role in this morphogenesis. By visualizing the distribution of collagen fibrils and by changing the concentration of collagen in the gland, we have developed a new hypothesis which emphasizes the mechanical role of mesenchyme in epithelial cleft formation. Precise mechanisms for the involvement of these molecules have not been elucidated, yet it is now clear that knowledge of the function of the extracellular matrix components is a prerequisite for understanding the epithelial-mesenchymal interactions.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bies.950110602
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  • 20
    Electronic Resource
    Electronic Resource
    Carbon-13 NMR spectra of all-trans-N-retinylidene-n-butylamine as an analogue of the Schiff's base linkage-compound in visual pigment (1975)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 7 (1975), S. 485-487 
    Details
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Carbon-13 NMR spectra have been obtained for all-trans-N-retinylidene-n-butylamine as an analogue of the Schiff's base linkage compound in visual pigment. The chemical shift changes on going from all-trans-retinal1 to all-trans-N-retinylidene-n-butylamine are observed. These changes indicate the collapse of the bond alternation in conjugated polyene carbons, whereas N-protonation in all-trans-N-retinylidene-n-butylamine does not affect the bond alternation.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1270071006
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