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  • SOLAR PHYSICS  (11)
  • LIFE SCIENCES (GENERAL)  (6)
  • COMPUTER SYSTEMS  (2)
  • Aerospace Medicine  (1)
  • 1
    Publication Date: 2011-08-24
    Description: This study examined the association between local insulin-like growth factor I (IGF-I) overexpression and atrophy in skeletal muscle. We hypothesized that endogenous skeletal muscle IGF-I mRNA expression would decrease with hindlimb unloading (HU) in mice, and that transgenic mice overexpressing human IGF-I (hIGF-I) specifically in skeletal muscle would exhibit less atrophy after HU. Male transgenic mice and nontransgenic mice from the parent strain (FVB) were divided into four groups (n = 10/group): 1) transgenic, weight-bearing (IGF-I/WB); 2) transgenic, hindlimb unloaded (IGF-I/HU); 3) nontransgenic, weight-bearing (FVB/WB); and 4) nontransgenic, hindlimb unloaded (FVB/HU). HU groups were hindlimb unloaded for 14 days. Body mass was reduced (P 〈 0.05) after HU in both IGF-I (-9%) and FVB mice (-13%). Contrary to our hypothesis, we found that the relative abundance of mRNA for the endogenous rodent IGF-I (rIGF-I) was unaltered by HU in the gastrocnemius (GAST) muscle of wild-type FVB mice. High-level expression of hIGF-I peptide and mRNA was confirmed in the GAST and tibialis anterior (TA) muscles of the transgenic mice. Nevertheless, masses of the GAST and TA muscles were reduced (P 〈 0.05) in both FVB/HU and IGF-I/HU groups compared with FVB/WB and IGF-I/WB groups, respectively, and the percent atrophy in mass of these muscles did not differ between FVB and IGF-I mice. Therefore, skeletal muscle atrophy may not be associated with a reduction of endogenous rIGF-I mRNA level in 14-day HU mice. We conclude that high local expression of hIGF-I mRNA and peptide in skeletal muscle alone cannot attenuate unloading-induced atrophy of fast-twitch muscle in mice.
    Keywords: Aerospace Medicine
    Type: The American journal of physiology (ISSN 0002-9513); Volume 275; 3 Pt 1; E373-9
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  • 2
    Publication Date: 2013-08-31
    Description: The Hard X-Ray Burst Spectrometer (HXRBS) group at GSFC has developed and is maintaining a quick-look analysis system for solar flare hard x-ray data from the Burst and Transient Source Experiment (BATSE) on the recently launched Compton Gamma-Ray Observatory (GRO). The instrument consists, in part, of 8 large planar detectors, each 2025 sq cm, placed on the corners of the GRO spacecraft with the orientation of the faces being those of a regular octahedron. Although optimized for the detection of gamma-ray bursts, these detectors are far more sensitive than any previous spacecraft-borne hard x-ray flare instrumentation both for the detection of small microflares and the resolution of fine temporal structures. The data in this BATSE solar data base are from the discriminator large area (DISCLA) rates. From each of eight detectors there are hard x-ray data in four energy channels, 25-50, 50-100, 100-300, and greater than 300 keV with a time resolution of 1.024 seconds. These data are suitable for temporal correlation with data at other wavelengths, and they provide a first look into the BATSE and other GRO instrument flare data sets. The BATSE and other GRO principle investigator groups should be contacted for the availability of data sets at higher time or spectral resolution or at higher energies.
    Keywords: SOLAR PHYSICS
    Type: The Compton Observatory Science Workshop; p 457-468
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  • 3
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    In:  CASI
    Publication Date: 2013-08-31
    Description: Active Region 5395 produced an exceptional series of hard x ray bursts notable for their frequency, intensity, and impulsivity. Over the two weeks from March 6 to 19, 447 hard x ray flares were observed by the Hard X Ray Burst Spectrometer on Solar Maximum Mission (HXRBS/SMM), a rate of approx. 35 per day which exceeded the previous high by more than 50 percent. During one 5 day stretch, more than 250 flares were detected, also a new high. The three largest GOES X-flares were observed by HXRBS and had hard x ray rates over 100,000 s(exp -1) compared with only ten flares above 100,000(exp -1) during the previous nine years of the mission. An ongoing effort for the HXRBS group has been the correlated analysis of hard x ray data with flare data at other wavelengths with the most recent emphasis on those measurements with spatial information. During a series of bursts from AR 5395 at 1644 to 1648 UT on 12 March 1989, simultaneous observations were made by HXRBS and UVSP (Ultra Violet Spectrometer Polarimeter) on SMM, the two-element Owens Valley Radio Observatory (OVRO) interferometric array, and R. Canfield's H-alpha Echelle spectrograph at the National Solar Observatory at Sacramento Peak. The data show strong correlations in the hard x ray, microwave, and UV lightcurves. This event will be the subject of a combined analysis.
    Keywords: SOLAR PHYSICS
    Type: Max '91 Workshop 2: Developments in Observations and Theory for Solar Cycle 22; p 267-275
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  • 4
    Publication Date: 2016-03-09
    Description: The development and evaluation of fault-tolerant computer architectures and software-implemented fault tolerance (SIFT) for use in advanced NASA vehicles and potentially in flight-control systems are described in a collection of previously published reports prepared for NASA. Topics addressed include the principles of fault-tolerant multiprocessor (FTMP) operation; processor and slave regional designs; FTMP executive, facilities, acceptance-test/diagnostic, applications, and support software; FTM reliability and availability models; SIFT hardware design; and SIFT validation and verification.
    Keywords: COMPUTER SYSTEMS
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  • 5
    Publication Date: 2019-06-28
    Description: This event list is a comprehensive reference for all Hard X ray bursts detected with the Hard X Ray Burst Spectrometer on the Solar Maximum Mission from the time of launch on Feb. 14, 1980 to the end of the mission in Dec. 1989. Some 12,776 events were detected in the energy range 30 to 600 keV with the vast majority being solar flares. This list includes the start time, peak time, duration, and peak rate of each event.
    Keywords: SOLAR PHYSICS
    Type: NASA-TM-4332 , NAS 1.15:4332 , REPT-92B00009
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  • 6
    Publication Date: 2019-06-28
    Description: SIFT (Software Implemented Fault Tolerance) is an experimental, fault-tolerant computer system designed to meet the extreme reliability requirements for safety-critical functions in advanced aircraft. Errors are masked by performing a majority voting operation over the results of identical computations, and faulty processors are removed from service by reassigning computations to the nonfaulty processors. This scheme has been implemented in a special architecture using a set of standard Bendix BDX930 processors, augmented by a special asynchronous-broadcast communication interface that provides direct, processor to processor communication among all processors. Fault isolation is accomplished in hardware; all other fault-tolerance functions, together with scheduling and synchronization are implemented exclusively by executive system software. The system reliability is predicted by a Markov model. Mathematical consistency of the system software with respect to the reliability model has been partially verified, using recently developed tools for machine-aided proof of program correctness.
    Keywords: COMPUTER SYSTEMS
    Type: NASA-CR-172146 , NAS 1.26:172146
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  • 7
    Publication Date: 2019-06-28
    Description: Solar flare data from June 27, 1980 balloon-based observations were studied in terms of the hard X ray component. A temporal delay of 3 sec was observed for the X ray emissions above 235 keV. The delay occurred relative to the low-energy electrons and indicated a second acceleration stage. An estimation of the acceleration rate of the first-order Fermi process operating in a closed flare loop was found to be in agreement with the resulting data, including the acceleration of both protons and relativistic electrons. Additional support for the first-order Fermi process is noted in the fact that flares generally occur in magnetic loops, a condition which allows energetic particles to continually interact with the upward moving shock fronts. A correlation has also been observed between the delay times and the H-alpha areas, encouraging the interpretation that the delay times are the shock transit times.
    Keywords: SOLAR PHYSICS
    Type: Astrophysical Journal; vol. 267
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  • 8
    Publication Date: 2019-06-28
    Description: High-resolution (approximately 1 keV FWHM) spectral measurements from 13 to 300 keV of a solar flare hard X-ray burst observed on 1980 June 27 by a balloon-borne array of cooled germanium planar detectors are presented. At energies below about 35 keV, a new component of solar flare hard X-rays is identified. This component is characterized by an extremely steep spectrum which fits closely to that from a Maxwellian electron distribution with a maximum temperature of about 34 x 10 to the 6th K and an emission measure of 2.9 x 10 to the 48th per cu cm. This hot isothermal component appears at the peak of the normal power-law-like impulsive X-ray burst component, and it remains isothermal and dominates the X-ray emission below about 30 keV through the decay of the flare event.
    Keywords: SOLAR PHYSICS
    Type: Astrophysical Journal; vol. 251
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  • 9
    Publication Date: 2019-07-13
    Description: This report describes work performed under contract NAS5-32584 for Phase 3 of the Compton Gamma Ray Observatory (CGRO) from 1 November 1993 through 1 November 1994. We have made spectral observations of the hard x-ray and gamma-ray bremsstrahlung emissions from solar flares using the Burst and Transit Source Experiment (BASTE) on CGRO. These measurements of their spectrum and time profile provided valuable information on the fundamental flare processes of energy release, particle acceleration, and energy transport. Our scientific objective was to study both the thermal and non-thermal sources of solar flare hard x-ray and gamma-ray emission.
    Keywords: SOLAR PHYSICS
    Type: NASA-CR-189436 , NAS 1.26:189436 , IHK-341-03
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  • 10
    Publication Date: 2019-07-13
    Description: All of the available molecular data support the theory that the chloroplasts of eukaryote cells were originally free-living blue-greens. Of great interest is what the relationships are between contemporary types of blue-greens and eukaryote chloroplasts and whether the chloroplasts of the various eukaryotes are the result of one or more than one symbiosis. By combining information from phylogenetic trees based on cytochrome c6 and 2Fe-2S ferredoxin sequences, it is shown that the chloroplasts of a number of eukaryote algae as well as the protist Euglena are polyphyletic; the chloroplasts of green algae and the higher plants may be the result of a single symbiosis.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: Origin of life; Jun 22, 1980 - Jun 27, 1980; Jerusalem; Israel
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