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  • Adrenergic beta receptor blockaders  (1)
  • myocardial infarction  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    The possible effect of long-term high plasma levels of phenytoin on mortality after acute myocardial infarction (1973)
    Springer
    European journal of clinical pharmacology 5 (1973), S. 138-144 
    Details
    ISSN: 1432-1041
    Keywords: Phenytoin ; plasma level ; myocardial infarction ; treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In a group of patients studied for 12 months after myocardial infarction plasma levels of phenytoin were measured whilst the patients received phenytoin 300–400 mg per day or placebo therapy. Two sub-groups of patients treated with phenytoin were identified, based on the steady state level of plasma phentyoin concentration. Patients who had achieved phenytoin plasma concentrations of 10 µg/ml or above, had a significantly lower mortality than patients who had plasma concentration below this level or than patients treated with placebo. Ventricular premature beats occurred significantly less often in the phenytoin treated group than among the comparative group of patients. The significance of these findings is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00564893
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  • 2
    Electronic Resource
    Electronic Resource
    The use of hypoglycaemic and cardiovascular drugs in 582 patients with diabetes mellitus (1993)
    Springer
    Pharmacy world & science 15 (1993), S. 128-131 
    Details
    ISSN: 1573-739X
    Keywords: Adrenergic beta receptor blockaders ; Cardiovascular agents ; Diabetes mellitus ; Drug utilization ; Quality of health care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The medication of 582 patients taking insulin or oral hypoglycaemic agents has been analysed. A characterization is given of the patients and their. antidiabetic medication. Subsequently, a description of the use of cardiovascular drugs, in comparison with an age-matched control group, is presented. The diabetic population investigated has an average age of 67 years. Most cardiovascular agents, with the exception of thiazide diuretics, are used to a larger extent in the diabetic group in comparison with the control group. Non-selectiveβ-blockers, possibly hazardous in patients with diabetes mellitus, appear to be prescribed without restriction in the diabetic patients investigated. The results of this study suggest that the choice of drugs for the treatment of cardiovascular co-morbidity in patients with diabetes mellitus can be improved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02113941
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    Paper (German National Licenses)
    Fulltext
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