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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Research in engineering design 6 (1994), S. 1-13 
    ISSN: 1435-6066
    Keywords: Concurrent engineering ; Design management ; Design process improvement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Technology
    Notes: Abstract This research is aimed at structuring complex design projects in order to develop better products more quickly. We use a matrix representation to capture both the sequence of and the technical relationships among the many design tasks to be performed. These relationships define the “technical structure” of a project, which is then analyzed in order to find alternative sequences and/or definitions of the tasks. Such improved design procedures offer opportunities to speed development progress by streamlining the inter-task coordination. After using this technique to model design processes in several organizations, we have developed a design management strategy which focuses attention on the essential information transfer requirements of a technical project.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2004-01-31
    Description: Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rendulic, Snjezana -- Jagtap, Pratik -- Rosinus, Andrea -- Eppinger, Mark -- Baar, Claudia -- Lanz, Christa -- Keller, Heike -- Lambert, Carey -- Evans, Katy J -- Goesmann, Alexander -- Meyer, Folker -- Sockett, R Elizabeth -- Schuster, Stephan C -- New York, N.Y. -- Science. 2004 Jan 30;303(5658):689-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institute for Developmental Biology, 72076 Tubingen, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14752164" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Amino Acids/metabolism ; Bacterial Adhesion/genetics ; Bacterial Proteins/biosynthesis/genetics/metabolism ; Bdellovibrio/cytology/*genetics/*growth & development/physiology ; Biological Transport ; Cell Membrane/metabolism ; Computational Biology ; Cytosol/metabolism ; Fimbriae, Bacterial/genetics/physiology ; Flagella/genetics/physiology ; Gene Transfer, Horizontal ; Genes, Bacterial ; *Genome, Bacterial ; Genomics ; Gram-Negative Bacteria ; Hydrolases/genetics/metabolism ; Membrane Transport Proteins/genetics/metabolism ; Open Reading Frames ; Peptidoglycan/metabolism ; Sequence Analysis, DNA
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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