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  • ASTROPHYSICS  (1)
  • Drug utilisation  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    European journal of clinical pharmacology 55 (2000), S. 765-771 
    ISSN: 1432-1041
    Schlagwort(e): Key words Nursing home ; Drug utilisation ; Elderly
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Abstract Objective: To quantify and evaluate drug utilisation in a sample of Dutch nursing homes. Methods: A retrospective analysis of computerised medication data of 2355 residents aged 65 years and over from six nursing homes in the Netherlands was performed. For each therapeutic drug group, the number of users was determined. The ten therapeutic groups used most frequently were investigated further. For these, patient characteristics, use of therapeutic subgroups, the average daily dosages and the chronicity of drug use were determined. Chronicity was expressed as the percentage of treatment days divided by the number of residents' days in the nursing home. Results: During the study period, 89%, 77% and 56% of the study population used a drug from the anatomical therapeutic chemical (ATC) main group N (nervous system), A (alimentary tract and metabolism) and C (cardiovascular system), respectively. Eight of the ten therapeutic drug groups prescribed most frequently were used for more than 50% of the time. In particular, psycholeptic drugs, diuretics and laxatives were used chronically (83%, 81%, and 80% of the nursing home stay, respectively). Except for a few drug groups, such as laxatives and diuretics, the prescribed daily dosages were relatively low. Twenty-eight percent of the residents received loop diuretics; these were prescribed in relatively high dosages. Conclusion: Drug utilisation in the nursing homes was high and many drugs were used chronically. In view of the risk of possible adverse effects and drug–drug interactions, the prescribing and dosage of psycholeptic drugs, laxatives, loop diuretics and ulcer-healing drugs should be re-evaluated, carefully.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 2019-07-13
    Beschreibung: The diffuse Galactic continuum gamma-ray emission has been studied using the full Sky Survey from COMPTEL on the Compton Observatory CGRO. The diffuse emission appears to be visible in the whole 0.75-30 MeV range covered by the instrument, although a considerable contribution from unresolved point sources cannot be excluded. A correlation analysis using HI and CO surveys of the Galaxy is used to derive the Galactic emissivity spectrum, and this is consistent with a smooth continuation to the spectrum at higher energies derived by a similar analysis of COS-B data. The apparent conversion factor from integrated CO temperature to molecular hydrogen column density can also be determined from the correlation analysis. The value obtained is consistent with results from COS-B and other non-gamma-ray methods. Calculations of the emissivity spectrum from bremsstrahlung from a cosmic-ray electron spectrum based on propagation models are compared with the observations.
    Schlagwort(e): ASTROPHYSICS
    Materialart: Astronomy and Astrophysics (ISSN 0004-6361); 292; 1; p. 82-91
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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