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  • 1
    Digitale Medien
    Digitale Medien
    Prostaglandin A"2 and Δ^1^2-prostaglandin J"2 induce apoptosis in L1210 cells
    Amsterdam : Elsevier
    FEBS Letters 321 (1993), S. 209-214 
    Details
    ISSN: 0014-5793
    Schlagwort(e): Antiproliferative activity ; Apoptosis ; DNA fragmentation ; Δ^1^2-prostaglandin J"2
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(93)80110-G
    Standort Signatur Erwartet Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 2
    Digitale Medien
    Digitale Medien
    Induction of apoptosis and c-myc in L1210 lymphocytic leukemia cells by adenosine (1994)
    Springer
    Journal of biomedical science 1 (1994), S. 154-157 
    Details
    ISSN: 1423-0127
    Schlagwort(e): Adenosine ; Adenosine deaminase deficiency ; Apoptosis ; c-myc ; DNA fragmentation ; Proto-oncogene ; L1210 lymphocytic leukemia cells ; Severe combined immunodeficiency syndrome
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract High concentrations of adenosine (Ado), when added to L1210 lymphocytic leukemia cells, resulted in apoptosis or programmed cell death. The apoptotic process was accompanied by distinct morphological changes including chromatin condensation and blebbing of plasma membranes. Extensive DNA fragmentation was correlated with Ado concentrations. Furthermore, apoptosis in these cells was preceded by an early but transient expression of c-myc proto-oncogene, and was not influenced by homocysteine thiolactone added to the cells. Since severe combined immunodeficiency (SCID) is associated with a deficiency of adenosine deaminase, leading to defects in both cellular and humoral immunity, Ado-induced apoptosis may thus be a contributing factor in the pathology of SCID.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02253342
    Standort Signatur Erwartet Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 3
    Digitale Medien
    Digitale Medien
    Propagation of nitromethane detonations in porous media (1995)
    Springer
    Shock waves 5 (1995), S. 115-119 
    Details
    ISSN: 1432-2153
    Schlagwort(e): Detonation ; Nitromethane ; Porous media ; Heterogeneous explosive
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik , Technik allgemein
    Notizen: Abstract The characteristics of the propagation of a detonation in chemically sensitized nitromethane in a dense porous medium are investigated. By introducing liquid NM+15% (by weight) DETA into densely packed beds of solid spherical glass beads 66μm to 2.4 mm in diameter, a highly heterogeneous explosive mixture is obtained. The critical (i.e., failure) charge diameter of this mixture is systematically measured in unconfined charges over a wide range of bead sizes. Velocity measurements are also made for the various charges. It is found that there exists a critical bead size above which the critical diameter decreases with increasing bead size and below which it decreases with decreasing bead size. This result indicates an abrupt change in the mechanism of propagation at the critical bead size. Velocity measurements further support this by emphasizing the different behavior above and below the critical point.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02425043
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Transition from fast deflagration to detonation under the influence of periodic longitudinal perturbations (1995)
    Springer
    Shock waves 5 (1995), S. 159-167 
    Details
    ISSN: 1432-2153
    Schlagwort(e): Detonation ; Transition ; Deflagration ; Pulsating ; Longitudinal ; Instability
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik , Technik allgemein
    Notizen: Abstract A computational and experimental investigation have been carried out to study deflagration to detonation transition under the influence of periodic longitudinal perturbations. The fast deflagration prior to transition is obtained by suppressing the oscillatory structure of a detonation first. In the one-dimensional computational study, the subsequent re-transition is stimulated using periodic density perturbations. The optimal perturbation period to induce transition is of the order of the rea ction time of the detonation structure. In the experiments, re-transition is stimulated using periodic wire screens placed across the channel. The gas mixture used is 2C2H2+5O2+75%Ar. Laser stroboscopic photography showed the generation of longitudinal pressure waves as the leading shock passes through the wire screens. The interactions of the pressure waves with the leading shock and the reaction zone establish coupling for transition to occur. The computational and experimental studies showed that the time required for transition to take place is dependent on the frequency of the applied perturbation. The present results indicate the need to examine deflagration to detonation transition from the point of view of the formation of an organized oscillatory system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01435523
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    facet.materialart.
    Unbekannt
    Cryogenic and thermal design for the Superfluid Helium On-Orbit Transfer (SHOOT) experiment (1988)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-07-13
    Beschreibung: The analysis and trade-offs of the external thermal design of the two 200-liter dewars required in the SHOOT experiment to extend space mission life by superfluid helium replenishment are discussed. Also considered are the support electronics and the optimization and prediction of the performance of the dewar and cryostat assemblies. Particular attention is given to the ground-hold and standby performance of the dewars, along with the temperature of the helium bath during high-flow-rate helium transfers.
    Schlagwort(e): ASTRONAUTICS (GENERAL)
    Materialart: Advances in cryogenic engineering.; Jun 14, 1987 - Jun 18, 1987; Saint Charles, IL; United States
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
  • 6
    facet.materialart.
    Unbekannt
    Comparison of SIRTF dewar performance in the 900 km and 100,000 km orbits (1990)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-07-13
    Beschreibung: Feasibility studies showed that the Space Infrared Telescope Facility (SIRTF) can be launched into a 100,000-km high earth orbit (HEO) using a Titan/Centaur launch vehicle. This paper compares the performance of an all-superfluid helium dewar system for SIRTF under conditions of the LEO (900-km) and the HEO missions. Results show that the SIRTF all-superfluid He dewar can achieve a 5-yr lifetime for the 100,000 km HEO mission, with 20 percent margin. Methods to achieve further enhancement of dewar lifetime for the HEO mission are suggested.
    Schlagwort(e): ASTRONAUTICS (GENERAL)
    Materialart: 1989 Cryogenic Engineering Conference; Jul 24, 1989 - Jul 28, 1989; Los Angeles, CA; United States
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    NASA TECHNICAL REPORTS
  • 7
    facet.materialart.
    Unbekannt
    Pump performance requirement for the liquid helium orbital resupply tanker (1988)
    In:  Other Sources
    Details
    Publikationsdatum: 2019-07-13
    Beschreibung: The Liquid Helium Orbital Resupply Tanker (currently renamed to Superfluid Helium Tanker) will greatly enhance the lifetime of the space missions which require superfluid helium. The Superfluid Helium Tanker pump performance requirement is driven by the superfluid helium replenishment needs of the Space Infrared Telescope Facility (SIRTF). SIRTF is one of the space missions which will require on-orbit superfluid helium resupply in the 1990s. The Superfluid Helium Tanker will carry at least 10,000 L of superfluid helium and provide a minimum pump head of 170 torr (0 to 200 L/h) to cool SIRTF from 150 to 2 K. When the SIRTF tank starts to collect liquid, a minimum flow rate of 300 L/h with a pump head of 60 torr is required to fill the 4000-liter tank.
    Schlagwort(e): ASTRONAUTICS (GENERAL)
    Materialart: Advances in cryogenic engineering.; Jun 14, 1987 - Jun 18, 1987; Saint Charles, IL; United States
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
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