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Platyphylloside: Metabolism and digestibility reductionin vitro (1995)

Sunnerheim-Sjöberg, Kerstin ; Knutsson, Per-Göran

Springer

Journal of chemical ecology 21 (1995), S. 1339-1348

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ISSN: 1573-1561

Keywords: Phenols ; platyphylloside ; 5-hydroxy-3-platyphyllone ; 3-platyphyllone ; centrolobol ; metabolites ; digestibility ; rumen liquor ; birch

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract The metabolism of platyphylloside [(5S)-5-hydroxy-1,7-bis-(4-hydroxyphenyl)-3-heptanone-5-O-β-d-glucopyranosidel]—known to reduce digestibility—was studiedin vitro in sheep rumen liquor. Platyphylloside is hydrolyzed to 5-hydroxy-3-platyphyllone [(5S)-5-hydroxy-1,7-bis-(4-hydroxyphenyl)-3-heptanone], which is reduced to centrolobol [1,7-bis-(4-hydroxyphenyl)-3-heptanol], via 3-platyphyllone [7-bis-(4-hydroxyphenyl)-3-heptanone]. The digestibility-reducing effect was shown to be correlated with the concentration of centrolobol.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02027566

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