Publication Date:
1978-04-28
Description:
Multicellular masses of the cellular slime mold Dictyostelium discoideum, under conditions which ordinarily suppress cell differentiation, develop clusters of stalk cells and spore cells when implanted with Sephadex particles that had been soaked in 5 X 10(-3)M cyclic adenosine monophosphate (AMP). A possible relation exists between oxygen gradients, cyclic AMP gradients, and the pattern of morphogenesis and cell differentiation during fruiting.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Feit, I N -- Fournier, G A -- Needleman, R D -- Underwood, M Z -- New York, N.Y. -- Science. 1978 Apr 28;200(4340):439-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/205945" target="_blank"〉PubMed〈/a〉
Keywords:
Cell Differentiation/drug effects
;
Cyclic AMP/*pharmacology
;
Dictyostelium/*cytology
;
Morphogenesis/drug effects
;
Myxomycetes/*cytology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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