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  • 10-86; 10-94; 10-95; Acarinina collactea, δ13C; Acarinina collactea, δ18O; Acarinina mckannai, δ13C; Acarinina mckannai, δ18O; Acarinina nitida, δ13C; Acarinina nitida, δ18O; Chiloguembelina midwayensis, δ13C; Chiloguembelina midwayensis, δ18O; Deep Sea Drilling Project; DRILL; Drilling/drill rig; DSDP; DSDP/ODP/IODP sample designation; Event label; Foraminifera, benthic δ13C; Foraminifera, benthic δ18O; Gavelinella spp., δ13C; Gavelinella spp., δ18O; Glomar Challenger; Gulf of Mexico/BENCH; Gulf of Mexico/SCARP; Leg10; Morozovella subbotinae, δ13C; Morozovella subbotinae, δ18O; Morozovella uncinata, δ13C; Morozovella uncinata, δ18O; Morozovella velascoensis, δ13C; Morozovella velascoensis, δ18O; Nuttallides spp., δ13C; Nuttallides spp., δ18O; Planktic foraminifera zone; Planorotalites compressus, δ13C; Planorotalites compressus, δ18O; Planorotalites pseudomenardii, δ13C; Planorotalites pseudomenardii, δ18O; Robulus spp., δ13C; Robulus spp., δ18O; Sample code/label; Subbotina trilocularis, δ13C; Subbotina trilocularis, δ18O; Subbotina triloculinoides, δ13C; Subbotina triloculinoides, δ18O  (1)
  • 25-hydroxycholesterol
Collection
Keywords
Publisher
Years
  • 1
    Electronic Resource
    Electronic Resource
    α-tocopherol inhibits oxidative stress induced by cholestanetriol and 25-hydroxycholesterol in porcine ovarian granulosa cells (1999)
    Springer
    Molecular and cellular biochemistry 194 (1999), S. 217-225 
    Details
    ISSN: 1573-4919
    Keywords: cholestanetriol ; 25-hydroxycholesterol ; lipid peroxidation ; antioxidant enzymes ; α-tocopherol ; ovarian granulosa cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The cytotoxicity of oxysterols including 7-ketocholesterol, α-epoxide, cholestanetriol and 25-hydroxycholesterol and the possible protecting effect of α-tocopherol on cholestanetriol and 25-hydroxycholesterol-induced cytotoxicity were investigated in primary cultures of porcine ovarian granulosa cells. Cell viability as determined by % trypan blue staining and mitochondrial function as determined using 3-[4,5-dimethylthiazol-2-yl]-2,5- diphenyltetrazolium bromide (MTT) reduction were decreased significantly after 24 h exposure to 2.5 μM α-epoxide, cholestanetriol and 25-hydroxycholesterol. 7-ketocholesterol (2.5 μM) did not affect cell viability or mitochondrial function under the same culture conditions. The specific activities of catalase and superoxide dismutase, two antioxidant defense enzymes were increased significantly (p 〈 0.01) following 24 h exposure to 2.5 μM concentrations of cholestanetriol while only superoxide dismutase was increased in 25-hydroxycholesterol-treated cells (p 〈 0.001). Specific activity of glutathione peroxidase was unchanged relative to control cells. Levels of thiobarbituric acid reactive substances remained unchanged after exposure to 7-ketocholesterol, α-epoxide, cholestanetriol, 25-hydroxycholesterol and cholesterol. Administration of 1 μM α-tocopherol to the culture medium significantly improved cell viability and restored both superoxide dismutase and catalase activities to control levels in cholestanetriol -treated cells and only superoxide dismutase in 25-hydroxycholesterol-treated cells. These studies suggest that the cytotoxic nature of physiologically relevant concentrations of cholestanetriol and 25-hydroxycholesterol in granulosa cells is in part due to oxidative stress, but it may be reduced in the presence of a-tocopherol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006967219894
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    Paper (German National Licenses)
    Fulltext
  • 2
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    Unknown
    (Table 4) Stable carbon and oxygen isotope ratios of foraminifera from DSDP Leg 10 (1979)
    PANGAEA
    Details
    Publication Date: 2023-07-10
    Keywords: 10-86; 10-94; 10-95; Acarinina collactea, δ13C; Acarinina collactea, δ18O; Acarinina mckannai, δ13C; Acarinina mckannai, δ18O; Acarinina nitida, δ13C; Acarinina nitida, δ18O; Chiloguembelina midwayensis, δ13C; Chiloguembelina midwayensis, δ18O; Deep Sea Drilling Project; DRILL; Drilling/drill rig; DSDP; DSDP/ODP/IODP sample designation; Event label; Foraminifera, benthic δ13C; Foraminifera, benthic δ18O; Gavelinella spp., δ13C; Gavelinella spp., δ18O; Glomar Challenger; Gulf of Mexico/BENCH; Gulf of Mexico/SCARP; Leg10; Morozovella subbotinae, δ13C; Morozovella subbotinae, δ18O; Morozovella uncinata, δ13C; Morozovella uncinata, δ18O; Morozovella velascoensis, δ13C; Morozovella velascoensis, δ18O; Nuttallides spp., δ13C; Nuttallides spp., δ18O; Planktic foraminifera zone; Planorotalites compressus, δ13C; Planorotalites compressus, δ18O; Planorotalites pseudomenardii, δ13C; Planorotalites pseudomenardii, δ18O; Robulus spp., δ13C; Robulus spp., δ18O; Sample code/label; Subbotina trilocularis, δ13C; Subbotina trilocularis, δ18O; Subbotina triloculinoides, δ13C; Subbotina triloculinoides, δ18O
    Type: Dataset
    Format: text/tab-separated-values, 58 data points
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    DATA PANGAEA
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