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  • 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk  (5)
  • 04. Solid Earth::04.07. Tectonophysics::04.07.06. Subduction related processes  (2)
  • 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring  (2)
  • Auckland Volcanic Field  (2)
  • BET_EF code  (2)
  • Polyploidy
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 40 (1995), S. 110-115 
    ISSN: 1040-452X
    Keywords: Aneuploidy ; Cryoprotectant ; Fertility ; Polyploidy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to determine the different stages in the complete freezing-thawing process which are deleterious for the oocytes and the subsequent zygotes. IVF assays showed that DMSO decreased the fertility of oocytes, whereas cooling to 0°C had no effect. DMSO, used at 0°C, was less deleterious for oocytes. Thus, the prefreezing manipulations seem to be important for the quality and fertility of oocytes. However, neither DMSO nor cooling increased the incidence of chromosomal abnormalities in embryos obtained from inseminated exposed oocytes. Therefore, the increased frequency of polyploidy observed in embryos after the cryopreservation of mouse oocytes must correspond to disruption occurring during the freezing-thawing process.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2021-06-25
    Description: The Auckland Volcanic Field (AVF) is a young basaltic field that lies beneath the urban area of Auckland, New Zealand’s largest city. Over the past 250,000 years the AVF has produced at least 49 basaltic centers; the last eruption was only 600 years ago. In recognition of the high risk associated with a possible future eruption in Auckland, the New Zealand government ran Exercise Ruaumoko in March 2008, a test of New Zealand’s nation-wide preparedness for responding to a major disaster resulting from a volcanic eruption in Auckland City. The exercise scenario was developed in secret, and covered the period of precursory activity up until the eruption. During Exercise Ruaumoko we adapted a recently developed statistical code for eruption forecasting, namely BET_EF (Bayesian Event Tree for Eruption Forecasting), to independently track the unrest evolution and to forecast the most likely onset time, location and style of the initial phase of the simulated eruption. The code was set up before the start of the exercise by entering reliable information on the past history of the AVF as well as the monitoring signals expected in the event of magmatic unrest and an impending eruption. The average probabilities calculated by BET_EF during Exercise Ruaumoko corresponded well to the probabilities subjectively (and independently) estimated by the advising scientists (differences of few percentage units), and provided a sound forecast of the timing (before the event, the eruption probability reached 90%) and location of the eruption. This application of BET_EF to a volcanic field that has experienced no historical activity and for which otherwise limited prior information is available shows its versatility and potential usefulness as a tool to aid decision-making for a wide range of volcano types. Our near real-time application of BET_EF during Exercise Ruaumoko highlighted its potential to clarify and possibly optimize decision-making procedures in a future AVF eruption crisis, and as a rational starting point for discussions in a scientific advisory group. It also stimulated valuable scientific discussion around how a future AVF eruption might progress, and highlighted areas of future volcanological research that would reduce epistemic uncertainties through the development of better input models.
    Description: Published
    Description: 185–204
    Description: 4.3. TTC - Scenari di pericolosità vulcanica
    Description: JCR Journal
    Description: reserved
    Keywords: Auckland Volcanic Field ; Eruption forecasting ; Bayesian Event Tree ; Ruaumoko ; Disaster exercise ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Publication Date: 2020-11-18
    Description: Fragility curves (FCs) constitute an emerging tool for the seismic risk assessment of all elements at risk. They express the probability of a structure being damaged beyond a specific damage state for a given seismic input motion parameter, incorporating the most important sources of uncertainties, that is, seismic demand, capacity and definition of damage states. Nevertheless, the implementation of FCs in loss/risk assessments introduces other important sources of uncertainty, related to the usually limited knowledge about the elements at risk (e.g., inventory, typology). In this paper, within a Bayesian framework, it is developed a general methodology to combine into a single model (Bayesian combined model, BCM) the information provided by multiple FC models, weighting them according to their credibility/ applicability, and independent past data. This combination enables to efficiently capture inter-model variability (IMV) and to propagate it into risk/loss assessments, allowing the treatment of a large spectrum of vulnerability-related uncertainties, usually neglected. As case study, FCs for shallow tunnels in alluvial deposits, when subjected to transversal seismic loading, are developed with two conventional procedures, based on a quasi-static numerical approach. Noteworthy, loss/risk assessments resulting from such conventional methods show significant unexpected differences. Conventional fragilities are then combined in a Bayesian framework, in which also probability values are treated as random variables, characterized by their probability density functions. The results show that BCM efficiently projects the whole variability of input models into risk/loss estimations. This demonstrates that BCM is a suitable framework to treat IMV in vulnerability assessments, in a straightforward and explicit manner.
    Description: Published
    Description: 723-746
    Description: 4.1. Metodologie sismologiche per l'ingegneria sismica
    Description: JCR Journal
    Description: open
    Keywords: Fragility curves ; Bayesian approach ; Epistemic uncertainty ; Inter-model variability ; Seismic risk ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 4
    Publication Date: 2021-03-18
    Description: This article presents an integrated approach for the probabilistic systemic risk analysis of a road network considering spatial seismic hazard with correlation of ground motion intensities, vulnerability of the network components, and the effect of interactions within the network, as well as, between roadway components and built environment to the network functionality. The system performance is evaluated at the system level through a global connectivity performance indicator, which depends on both physical damages to its components and induced functionality losses due to interactions with other systems. An object-oriented modeling paradigm is used, where the complex problem of several interacting systems is decomposed in a number of interacting objects, accounting for intra- and interdependencies between and within systems. Each system is specified with its components, solving algorithms, performance indicators and interactions with other systems. The proposed approach is implemented for the analysis of the road network in the city of Thessaloniki (Greece) to demonstrate its applicability. In particular, the risk for the road network in the area is calculated, specifically focusing on the short-term impact of seismic events (just after the earthquake). The potential of road blockages due to collapses of adjacent buildings and overpass bridges is analyzed, trying to individuate possible criticalities related to specific components/subsystems. The application can be extended based on the proposed approach, to account for other interactions such as failure of pipelines beneath the road segments, collapse of adjacent electric poles, or malfunction of lighting and signaling systems due to damage in the electric power network.
    Description: Published
    Description: 524–540
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: JCR Journal
    Description: restricted
    Keywords: Systemic vulnerability ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 5
    Publication Date: 2021-05-12
    Description: Any trustworthy probabilistic seismic hazard analysis (PSHA) has to account for the intrinsic variability of the system (aleatory variability) and the limited knowledge of the system itself (epistemic uncertainty). The most popular framework for this purpose is the logic tree. Notwithstanding its vast popularity, the logic tree outcomes are still interpreted in two different and irreconcilable ways. In one case, practitioners claim that the mean hazard of the logic tree is the hazard and the distribution of all outcomes does not have any probabilistic meaning. On the other hand, other practitioners describe the seismic hazard using the distribution of all logic tree outcomes. In this paper, we explore in detail the reasons of this controversy about the interpretation of logic tree, showing that the distribution of all outcomes is more appropriate to provide a joined full description of aleatory variability and epistemic uncertainty. Then, we provide a more general framework - that we name ensemble modeling - in which the logic tree outcomes can be embedded. In this framework, the logic tree is not a classical probability tree, but it is just a technical tool that samples epistemic uncertainty. Ensemble modeling consists of inferring the parent distribution of the epistemic uncertainty from which this sample is drawn. Ensemble modeling offers some remarkable additional features. First, it allows a rigorous and meaningful validation of any PSHA; this is essential if we want to keep PSHA into a scientific domain. Second, it provides a proper and clear description of the aleatory variability and epistemic uncertainty that can help stakeholders to appreciate the whole range of uncertainties in PSHA. Third, it may help to reduce the computational time when the logic tree becomes computationally intractable because of the too many branches.
    Description: Published
    Description: 2151-2159
    Description: 1SR. TERREMOTI - Servizi e ricerca per la Società
    Description: JCR Journal
    Description: reserved
    Keywords: seismic hazard ; logic tree ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
    Publication Date: 2017-04-04
    Description: Reliable forecasting of the next eruption at Vesuvius is the main scientific factor in defining effective strategies to reduce volcanic risk in one of the most dangerous volcanic areas of the world. In this paper, we apply a recently developed probabilistic code for eruption forecasting to new and independent historical data related to the pre-eruptive phase of the 1631 eruption. The results obtained point out three main issues: (1) the importance of “cold” historical data (according to Guidoboni 2008) related to pre-eruptive phases for evaluating forecasting tools and possibly refining them; (2) the BET_EF code implemented for Vesuvius would have forecasted the 1631 eruption satisfactorily, marking different stages of the pre-eruptive phase; (3) the code shows that pre-eruptive signals that significantly increase the probability of eruption were likely detected more than 2 months before the event.
    Description: Published
    Description: 729-745
    Description: 4.3. TTC - Scenari di pericolosità vulcanica
    Description: JCR Journal
    Description: reserved
    Keywords: Cold historical data ; Vesuvius ; 1631 eruption ; BET_EF code ; Eruption forecasting ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 7
    Publication Date: 2017-04-04
    Description: The Auckland Volcanic Field (AVF) is a young basaltic field that lies beneath the urban area of Auckland, New Zealand’s largest city. Over the past 250,000 years the AVF has produced at least 49 basaltic centers; the last eruption was only 600 years ago. In recognition of the high risk associated with a possible future eruption in Auckland, the New Zealand government ran Exercise Ruaumoko in March 2008, a test of New Zealand’s nation-wide preparedness for responding to a major disaster resulting from a volcanic eruption in Auckland City. The exercise scenario was developed in secret, and covered the period of precursory activity up until the eruption. During Exercise Ruaumoko we adapted a recently developed statistical code for eruption forecasting, namely BET_EF (Bayesian Event Tree for Eruption Forecasting), to independently track the unrest evolution and to forecast the most likely onset time, location and style of the initial phase of the simulated eruption. The code was set up before the start of the exercise by entering reliable information on the past history of the AVF as well as the monitoring signals expected in the event of magmatic unrest and an impending eruption. The average probabilities calculated by BET_EF during Exercise Ruaumoko corresponded well to the probabilities subjectively (and independently) estimated by the advising scientists (differences of few percentage units), and provided a sound forecast of the timing (before the event, the eruption probability reached 90%) and location of the eruption. This application of BET_EF to a volcanic field that has experienced no historical activity and for which otherwise limited prior information is available shows its versatility and potential usefulness as a tool to aid decision-making for a wide range of volcano types. Our near real-time application of BET_EF during Exercise Ruaumoko highlighted its potential to clarify and possibly optimize decision-making procedures in a future AVF eruption crisis, and as a rational starting point for discussions in a scientific advisory group. It also stimulated valuable scientific discussion around how a future AVF eruption might progress, and highlighted areas of future volcanological research that would reduce epistemic uncertainties through the development of better input models.
    Description: In press
    Description: 4.3. TTC - Scenari di pericolosità vulcanica
    Description: JCR Journal
    Description: reserved
    Keywords: Auckland Volcanic Field ; Eruption forecasting ; Bayesian Event Tree ; Ruaumoko ; Disaster exercise ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 8
    Publication Date: 2015-04-03
    Description: Eruption forecasting is a major goal in volcanology. Logically, but unfortunately, forecasting hazards related to non-magmatic unrest is too often overshadowed by eruption forecasting, although many volcanoes often pass through states of non-eruptive and non-magmatic unrest for various and prolonged periods of time. Volcanic hazards related to non-magmatic unrest can be highly violent and/or destructive (e.g., phreatic eruptions, secondary lahars), can lead into magmatic and eventually eruptive unrest, and can be more difficult to forecast than magmatic unrest, for various reasons. The duration of a state of non-magmatic unrest and the cause, type and locus of hazardous events can be highly variable. Moreover, non-magmatic hazards can be related to factors external to the volcano (e.g., climate, earthquake). So far, monitoring networks are often limited to the usual seismic-ground deformation-gas network, whereas recognizing indicators for non-magmatic unrest requires additional approaches. In this study we summarize non-magmatic unrest processes and potential indicators for related hazards. We propose an event-tree to classify non-magmatic unrest, which aims to cover all major hazardous outcomes. This structure could become useful for future probabilistic non-magmatic hazard assessments, and might reveal clues for future monitoring strategies.
    Description: Published
    Description: 17
    Description: 2V. Dinamiche di unrest e scenari pre-eruttivi
    Description: N/A or not JCR
    Description: open
    Keywords: Non-magmatic unrest ; Volcanic hazard ; Forecasting ; Volcanic surveillance ; Event tree ; 04. Solid Earth::04.08. Volcanology::04.08.06. Volcano monitoring ; 05. General::05.02. Data dissemination::05.02.03. Volcanic eruptions
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 9
    Publication Date: 2017-04-04
    Description: Reliable forecasting of the next eruption at Vesuvius is the main scientific ingredient to define effective strategies to reduce volcanic risk in one of the most dangerous volcanic areas around the world. In this paper, we apply a recently developed probabilistic code for eruption forecasting to new and independent historical data related to the pre-eruptive phase of the 1631 eruption. The results obtained point out three main issues: 1) the importance of “cold” historical data (according to Guidoboni 2008) related to pre-eruptive phases for evaluating forecasting tools and possibly refining them; 2) the BET_EF code implemented for Vesuvius would have forecast the 1631 eruption satisfactorily, marking different stages of the pre-eruptive phase; 3) the code shows that pre-eruptive signals that significantly increase the probability of eruption were likely detected more than two months before the event
    Description: In press
    Description: 4.3. TTC - Scenari di pericolosità vulcanica
    Description: JCR Journal
    Description: open
    Keywords: cold historical data ; Vesuvius ; 1631 eruption ; BET_EF code ; eruption forecasting ; 04. Solid Earth::04.08. Volcanology::04.08.08. Volcanic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 10
    Publication Date: 2017-04-04
    Description: Probabilistic tsunami hazard analysis (PTHA) relies on computationally demanding numerical simulations of tsunami generation, propagation, and non-linear inundation on high-resolution topo-bathymetric models. Here we focus on tsunamis generated by co-seismic sea floor dis- placement, that is, on Seismic PTHA (SPTHA). A very large number of tsunami simulations are typically needed to incorporate in SPTHA the full expected variability of seismic sources (the aleatory uncertainty). We propose an approach for reducing their number. To this end, we (i) introduce a simplified event tree to achieve an effective and consistent exploration of the seismic source parameter space; (ii) use the computationally inexpensive linear approximation for tsunami propagation to construct a preliminary SPTHA that calculates the probability of maximum offshore tsunami wave height (H Max) at a given target site; (iii) apply a two-stage filtering procedure to these ‘linear’ SPTHA results, for selecting a reduced set of sources and (iv) calculate ‘non-linear’ probabilistic inundation maps at the target site, using only the selected sources. We find that the selection of the important sources needed for approximating probabilistic inundation maps can be obtained based on the offshore HMax values only. The filtering procedure is semi-automatic and can be easily repeated for any target sites. We describe and test the performances of our approach with a case study in the Mediterranean that considers potential subduction earthquakes on a section of the Hellenic Arc, three target sites on the coast of eastern Sicily and one site on the coast of southern Crete. The comparison between the filtered SPTHA results and those obtained for the full set of sources indicates that our approach allows for a 75–80 per cent reduction of the number of the numerical simulations needed, while preserving the accuracy of probabilistic inundation maps to a reasonable degree.
    Description: Published
    Description: 574-588
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: JCR Journal
    Description: restricted
    Keywords: Tsunami ; Hazard ; Probabilistic ; Subduction ; Mediterranean ; SPTHA ; 04. Solid Earth::04.06. Seismology::04.06.02. Earthquake interactions and probability ; 04. Solid Earth::04.07. Tectonophysics::04.07.04. Plate boundaries, motion, and tectonics ; 04. Solid Earth::04.07. Tectonophysics::04.07.06. Subduction related processes
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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