ISSN:
0170-2041
Keywords:
HIV-1 Inhibition
;
Oxazole
;
γ-Pyrone
;
Polyangium spec.
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Guided by a biological screening with a cell assay, the first HIV-1 inhibitor from a gliding bacterium, phenoxan (1), was isolated. The structure of 1 was determined by spectroscopic methods to be a substituted oxazole-γ-pyrone, showing a remarkable similarity to aureothin (2) and spectinabilin (3).
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1991199101125
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