Publication Date:
1984-07-13
Description:
Cultures of human lymphocytes exposed in microgravity to the mitogen concanavalin A showed less than 3 percent of the activation of ground controls. This result supports the hypothesis, based on simulations at low g and experiments at high g, that microgravity depresses whereas high gravity enhances cell proliferation rates. The effects of gravity are particularly strong in cells undergoing differentiation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cogoli, A -- Tschopp, A -- Fuchs-Bislin, P -- New York, N.Y. -- Science. 1984 Jul 13;225(4658):228-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6729481" target="_blank"〉PubMed〈/a〉
Keywords:
Cell Differentiation
;
*Cell Physiological Phenomena
;
Concanavalin A/pharmacology
;
Humans
;
Lymphocyte Activation/drug effects
;
Lymphocytes/drug effects/physiology
;
Space Flight
;
*Weightlessness
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink
