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  • 1
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    Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase (1997)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1997-10-23
    Description: G1 cyclin-dependent kinase (Cdk)-triggered degradation of the S-phase Cdk inhibitor Sic1p has been implicated in the transition from G1 to S phase in the cell cycle of budding yeast. A multidimensional electrospray mass spectrometry technique was used to map G1 Cdk phosphorylation sites in Sic1p both in vitro and in vivo. A Sic1p mutant lacking three Cdk phosphorylation sites did not serve as a substrate for Cdc34p-dependent ubiquitination in vitro, was stable in vivo, and blocked DNA replication. Moreover, purified phosphoSic1p was ubiquitinated in cyclin-depleted G1 extract, indicating that a primary function of G1 cyclins is to tag Sic1p for destruction. These data suggest a molecular model of how phosphorylation and proteolysis cooperate to bring about the G1/S transition in budding yeast.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Verma, R -- Annan, R S -- Huddleston, M J -- Carr, S A -- Reynard, G -- Deshaies, R J -- R01 GM52466-01/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1997 Oct 17;278(5337):455-60.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology, Box 156-29, California Institute of Technology, Pasadena, CA 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9334303" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Anaphase-Promoting Complex-Cyclosome ; Cyclin G ; Cyclin-Dependent Kinase Inhibitor Proteins ; Cyclin-Dependent Kinases/*metabolism ; Cyclins/*metabolism ; DNA Replication ; Enzyme Inhibitors/metabolism ; Fungal Proteins/*metabolism ; G1 Phase ; Ligases/metabolism ; Molecular Sequence Data ; Mutagenesis ; Phenotype ; Phosphopeptides/metabolism ; Phosphorylation ; Recombinant Fusion Proteins/metabolism ; *S Phase ; *Saccharomyces cerevisiae Proteins ; *Ubiquitin-Protein Ligase Complexes ; Ubiquitin-Protein Ligases ; Ubiquitins/metabolism ; Yeasts/*cytology/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 2
    Electronic Resource
    Electronic Resource
    The allelic relationship of genes giving resistance to mungbean yellow mosaic virus in blackgram (1986)
    Springer
    Theoretical and applied genetics 72 (1986), S. 737-738 
    Details
    ISSN: 1432-2242
    Keywords: Blackgram ; Vigna mungo ; Allelic relationship ; Resistance genes ; Mungbean yellow mosaic virus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The allelic relationship of resistance genes for MYMV was studied in blackgram (V. mungo (L.) Hepper). The resistant donors to MYMV — ‘Pant U84’ and ‘UPU 2’, and their F1, F2 and F3 generations — were inoculated artificially using an insect vector, whitefly (Bemisia tabaci Genn.). The two recessive genes previously reported for resistance were found to be the same in both donors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00266537
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    Paper (German National Licenses)
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  • 3
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    Distribution of dust in W31 complex (1989)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: W31 is a H II region/molecular cloud complex in the galactic plane at a distance of 6 Kpc. This complex consists of two prominent radio continuum sources (G10.2-0.3 and G10.3-0.1) representing H II regions. An extended region covering both these H II regions was mapped in the Far IR (FIR) using the TIFR 1 m balloon-borne telescope with an angular resolution of approx. 1 min and a dynamic range of 100. The resulting flux density distribution at an effective wavelength of 160 microns is presented. The coadded IRAS survey scan data at 60 and 100 microns were deconvolved using a maximum entropy method to generate the flux density maps of the same region. These 60 and 100 micron maps are given and are briefly discussed.
    Keywords: ASTROPHYSICS
    Type: NASA, Ames Research Center, Interstellar Dust: Contributed Papers; p 199-200
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 4
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    Dust in a few southern H II regions (1989)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: The property of dust in four southern H II region/molecular cloud complexes (RCW 108, RCW 57, RCW 122, and G351.6-1.3) was discussed. These regions were observed at an effective wavelength of 150 micron using TIFR balloon borne 1 m telescope and deconvolved maps with a resolution of 1 min were obtained. The data were combined with other available data to derive the properties of the infrared emitting dust in these regions.
    Keywords: ASTROPHYSICS
    Type: NASA, Ames Research Center, Interstellar Dust: Contributed Papers; p 197-198
    Format: application/pdf
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  • 5
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    Far-infrared observations of Circinus and NGC 4945 galaxies (1990)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: Circinus and NGC 4945 are two galaxies luminous in the infrared and are characterized by compact non thermal radio nuclei, deep silicate absorption features and unusually strong water vapor maser luminosities. Moorwood and Glass (1984) have observed these galaxies extensively in the 1 to 20 micron range. In the far-infrared, observations up to 100 microns are available from the Infrared Astronomy Satellite (IRAS). In order to study the cool dust component of these galaxies, researchers observed them at 150 microns using the Tata Institute of Fundamental Research (TIFR) 100 cm balloon-borne telescope. Here, they report observations along with deconvolved maps at 50 and 100 microns obtained from the Chopped Photometric Channel (CPC) on board IRAS.
    Keywords: ASTROPHYSICS
    Type: NASA, Ames Research Center, The Interstellar Medium in External Galaxies: Summaries of Contributed Papers; p 86-88
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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