Publication Date:
1993-01-29
Description:
The highly nonrandom character of genomic DNA can confound attempts at modeling DNA sequence variation by standard stochastic processes (including random walk or fractal models). In particular, the mosaic character of DNA consisting of patches of different composition can fully account for apparent long-range correlations in DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Karlin, S -- Brendel, V -- GM10452-29/GM/NIGMS NIH HHS/ -- HG00335-04/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 1993 Jan 29;259(5095):677-80.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Mathematics, Stanford University, CA 94305.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8430316" target="_blank"〉PubMed〈/a〉
Keywords:
Analysis of Variance
;
Bacteriophage lambda/genetics
;
Base Composition
;
*Base Sequence
;
DNA/*genetics
;
Globins/genetics
;
Humans
;
Mathematics
;
Models, Theoretical
;
Plants, Toxic
;
Stochastic Processes
;
Tobacco/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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