Publication Date:
1978-06-09
Description:
No detectable adenosine deaminase activity was found in whole cells or 105,000g cytosol preparations of B-mix K-44/6 cells when either [3H]adenosine or [3H]arabinosyladenine was used as substrate. When grown in tissue culture medium supplemented with horse serum these cells provide a deaminase-free system not requiring the use of an adenosine deaminase inhibitor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shipman, C Jr -- Drach, J C -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1163-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/206965" target="_blank"〉PubMed〈/a〉
Keywords:
Adenosine/metabolism
;
Adenosine Deaminase/*deficiency
;
*Avian Sarcoma Viruses
;
*Cell Line
;
*Cell Transformation, Viral
;
Nucleoside Deaminases/*deficiency
;
Substrate Specificity
;
Vidarabine/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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