ALBERT

Keywords: *Biomedical Research ; Editorial Policies ; Federal Government ; *Government Regulation ; *National Institutes of Health (U.S.) ; Periodicals as Topic ; Politics ; Scientific Misconduct/*legislation & jurisprudence ; United States ; Universities

Keywords: *Biomedical Research ; Federal Government ; Government Regulation ; History, 20th Century ; Research/*standards ; Scientific Misconduct/*legislation & jurisprudence ; United States

Keywords: Acquired Immunodeficiency Syndrome/history/*microbiology ; *Biomedical Research ; *Ethics ; Federal Government ; *Government Regulation ; HIV/*isolation & purification ; History, 20th Century ; Humans ; *Internationality ; National Institutes of Health (U.S.) ; United States

Keywords: *Biomedical Research ; Federal Government ; *Fraud ; Government ; *Government Regulation ; Humans ; *National Institutes of Health (U.S.) ; *Politics ; Public Policy ; *Research ; *Research Personnel ; *Scientific Misconduct ; *Social Control, Formal ; United States

Keywords: *Biomedical Research ; *Crime ; Editorial Policies ; Federal Government ; *Fraud ; Government Regulation ; History, 20th Century ; National Institutes of Health (U.S.) ; Peer Review ; Periodicals as Topic ; *Publishing ; *Research ; United States ; *Vision, Ocular

Keywords: *Biomedical Research ; Crime/*legislation & jurisprudence ; Federal Government ; Fraud/*legislation & jurisprudence ; *Government Regulation ; History, 20th Century ; Publishing/*standards ; Records as Topic/standards ; Research/*standards ; Research Personnel

Keywords: Animals ; *Biomedical Research ; Federal Government ; Fraud/legislation & jurisprudence ; Gene Expression Regulation ; Genes, Immunoglobulin ; History, 20th Century ; Mice ; Mice, Transgenic ; Publishing/*standards ; Research/*standards ; Research Personnel ; United States

Keywords: *Biomedical Research ; *Fraud ; Humans ; *Research ; Research Personnel ; *Scientific Misconduct

Keywords: *Biomedical Research ; California ; *Cell Line ; *Human Body ; Humans ; Jurisprudence ; *Leukemia, Hairy Cell ; Male ; *Patents as Topic ; *Patient Rights ; *Spleen ; questions about an individual's rights of ownership in relation to body tissues ; that have been turned over for biomedical research but are subsequently used ; commercially. In 1976, John Moore had his spleen removed at the University of ; California, Los Angeles, in connection with his leukemia treatment. The ; university and researchers David Golde and Shirley Quan recently received a ; patent on the biologically interesting Mo cell line, which was derived from ; Moore's spleen cells. Moore's suit claims that the university misappropriated his ; tissues and that the researchers failed to obtain a valid informed consent ; because they did not formally tell him about the potential commercial ; applications of the cell line.

Keywords: *Biomedical Research ; California ; Cell Line ; *Human Body ; Humans ; *Jurisprudence ; Patents as Topic/legislation & jurisprudence ; *Patient Rights ; Spleen/cytology ; *Tissue and Organ Procurement ; Regents of the University of California on the grounds that two researchers at ; the Los Angeles campus took unfair advantage of him by misappropriating cells ; derived from his spleen in the course of leukemia therapy--cells that were then ; used in research that led to a patent. A federal court procedural hearing on 29 ; October 1984 yielded a ruling that the case will be heard in California state ; court, though it will probably be at least three years before a trial date can be ; scheduled. University officials and scientists see the case as an "outrageous" ; and legally unjustified attempt to assert a claim to the patent. Nevertheless, ; policy makers and university institutional review boards now face the question of ; whether, and how, consent forms should be rewritten to clarify the issue.