ISSN:
0749-1581
Schlagwort(e):
Isoxazolidine diastereomers
;
Configurational assignment
;
Regio- and stereo-chemical control
;
2D NMR
;
(1H-1H) COSY
;
(13C-1H) HETCOR DEPT NOEDS
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
(±)-4,5,5-Trimethyl-1-pyrroline-1-oxide reacted readily with ethyl 4,5,6,7-tetra-O-acetyl-trans-2,3-dehydro-2,3-dideoxy-L(-)-arabinoheptenoate in anhydrous benzene to give a mixture of two diastereomeric isoxazolidines, [2α,3β,3aα,5α]- and [2α,3β,3aα,5β]-ethyl hexahydro-2-(1,2,3,4- tetraacetoxybutyl)-5,6,6-trimethylpyrrolo[1,2- b] isoxazole-3-carboxylate. The structures and configurations of both diastereomers were determined through the use of the (1H-1H) COSY, (13C-1H) HETCOR and NOEDS techniques.
Zusätzliches Material:
2 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/mrc.1260290702
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