ISSN:
0025-116X
Schlagwort(e):
Chemistry
;
Polymer and Materials Science
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
,
Physik
Notizen:
The asymmetric sorbents A, B, C, and D were prepared by interaction of a chloromethylated styrene copolymer of the isoporous macronet type (5,5% of crosslinks) with the chiral amines (S)-1-phenylethylamine, (R)-1,2-propanediamine, and their derivatives. Resins A and B, based on 1-phenylethylamine, do not sorb Cu(II) ions, whereas resins C and D, based on 1,2-propanediamine saturated with Cu(II) ions, were successfully used for ligand-exchange chromatography of amino acids, showing higher affinity to aminodicarboxylic acids than to diaminocarboxylic acids. Sorbent D displays an enantioselectivity of α ≥ 1,5 towards amino acids like Ala, Abu, Ser, or Lys and provides quantitative resolution of enantiomers of some other amino acids. L-amino acids are retained longer by resins C and D than D-isomers.
Zusätzliches Material:
2 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/macp.1979.021800905
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