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  • Articles  (128)
  • Wiley-Blackwell  (128)
  • Biology  (95)
  • Mathematics  (22)
  • Architecture, Civil Engineering, Surveying  (9)
  • Natural Sciences in General  (2)
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  • Articles  (128)
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  • 1
    Electronic Resource
    Electronic Resource
    Production of indole alkaloids by surface immobilized C. roseus cells (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 35 (1990), S. 660-667 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A technique was developed to surface immobilize plant cells and was scaled up in laboratory size bioreactors. This technique was shown not to hinder the biosynthetic potential of Catharanthus roseus immobilized cells and to induce a partial release (300 μg/L) of serpentine into the culture medium contrary to suspension cultured cells. The release pattern seemed to follow the biosynthesis trends of the product. This release mechanism could be stimulated by a factor of 10 within 2 h by increasing the pH of the culture from 5.0 to 5.5.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260350703
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  • 2
    Electronic Resource
    Electronic Resource
    Surface immobilization of plant cells (1989)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 33 (1989), S. 293-299 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A novel technique has been developed to immobilize plant cells. The cells are deposited on a surface of manmade fibrous material that provides for strong binding of the plant tissue biomass growing in the submerged culture. The immobilized plant cells remain fully viable. Relatively uniform biomass loadings of up to 20 mg d.w. plant cells/cm2 support material have been attained. All plant cells from the inoculum suspension became attached within the first 24-48 h depending on the support matrix configuration and hydraulic culture conditions. The advantages and scale-up potential of this technique are discussed and compared to other culturing modes.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260330307
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  • 3
    Electronic Resource
    Electronic Resource
    Development of bioreactors for the culture of surface immobilized plant cells (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 35 (1990), S. 702-711 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The scaleup of the technique of plant cell surface immobilization was performed successfully in specifically designed laboratory size bioreactors. The immobilizing matrix was formed into a vertically wound spiral providing for a high immobilizing area-to-volume ratio (0.8-1.2 cm-1). A modified airlift and a mechanically stirred vessel delivered a best bioreactor performance characterized by low biomass frothing and highly efficient plant cell attachment and retention (≥96%). The growth of Catharanthus roseus cells investigated in these bioreactors was found not to be mass transfer limited. It required mild mixing and aeration levels (kLa ∼ 10-15 h-1). The biomass formation pattern of surface immobilized plant cells generally exhibited a linear growth phase followed by a stationary phase characterized by the presence of residual carbohydrates in the medium, contrary to suspension cultures. This behavior was found to depend on the plant cell type and/or line cultured, as well as on the inoculum age. The space restriction and unidirectional growth of the SIPC biofilm combined with the limited availability of essential intracellular nutrients rapidly accumulated from the medium by the stationary phase inoculated plant cells all likely contributed to the culture behavior.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260350707
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  • 4
    Electronic Resource
    Electronic Resource
    Letters to the editor (1981)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 17 (1981), S. 1740-1742 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620171112
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  • 5
    Electronic Resource
    Electronic Resource
    Hydrodynamic confficients of some heaving cylinders of arbitrary shape (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 13 (1978), S. 17-33 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The fluid forces acting on a uniform cylinder with an infinitely long axis, heaving in the free surface or an infinite ideal fluid, are described in terms of its ‘added mass’ and ‘damping coefficient’. The techniques of multipole expansion and multiparameter conformal transformation are adopted for such calculations and applied to shapes which cannot be adequately represented by the conventional, and more rudimentary, ‘Lewis form fit’. The shapes referred to are both relevant to ship bows, one being a ‘fine section’ and the other a ‘bulbous section’. The parameters which influence the accuracy of the solution are examined. Results for these two sections are computed and compared with results based on (a) the ‘Lewis form approximation’ and (b) the ‘Frank's close fit method’ which employs a singularity representation.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620130103
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  • 6
    Electronic Resource
    Electronic Resource
    A finite element approach to subsonic aerodynamics (1979)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 14 (1979), S. 665-679 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A study of the application of the Finite Element Method to compressible potential flows, typified by the airfoil problem, is undertaken. Some novel approaches, believed to simplify solution techniques, are presented.The solutions use two pseudo-variational integrals, appropriate to subsonic flows, and possessing a physical iterative basis. With constant-derivatives triangular elements formulated for cylindrical co-ordinates, accurate solutions are easily obtained for the flow over a circular cylinder. For arbitrary airfoils a simple mapping is used to transform them into near circles. An appropriate mesh is then constructed in the mapped plane. The paper then presents two solution approaches by which this non-linear problem is solved in both the near circle plane and the airfoil plane.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620140504
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  • 7
    Electronic Resource
    Electronic Resource
    On the species clinostomum heterostomum (1899)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 15 (1899), S. 697-710 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1050150305
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  • 8
    Electronic Resource
    Electronic Resource
    A comparison between the ultraviolet microscopy and the Feulgen staining of certain cells (1932)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 53 (1932), S. 189-199 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This paper describes ultraviolet (λ = 2750 A) photomicrographs of resting and dividing chicken macrophages and fibroblasts and of erythrocytes and lymphocytes. The structures found in these photographs are compared with the ones brought out in fixed material by Feulgen staining and found to be essentially similar in appearance. A preliminary series of ultraviolet pictures is also shown of a single fibroblast passing through several of its stages of division.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1050530107
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  • 9
    Electronic Resource
    Electronic Resource
    Some ultraviolet photomicrographs made with different wave lengths (1933)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933), S. 131-135 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Photomicrographs have been made of grasshopper spermatocytes using ultraviolet light of several wave lengths. For studying chromosomes this wave length should be between ca 2800 A and ca 2500 A. With higher frequencies the entire cell becomes strongly absorbing and relatively little detail is to be seen. All cell structures, including the chromosomes, are as transparent to λ = 3500 A and to longer ultraviolet waves as they are to visible light. The present experiments do not indicate the exact point between λ = 3500 A and λ = 2800 A at which the selective chromatin absorption commences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1050550108
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  • 10
    Electronic Resource
    Electronic Resource
    The hemorrhagic and hemopoietic nodules in the alar and interfemoral membranes of pizonyx vivesi (chiroptera)Financial support for publication was provided by funds derived from income on the endowment of the Horace H. Rackham School of Graduate Studies, University of Michigan. (1954)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 94 (1954), S. 439-471 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1050940302
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