Publikationsdatum:
2013-12-12
Beschreibung:
Ten new monoterpenoid indole alkaloids, ochroborines A and B ( 1 and 2 , resp.), 10-hydroxyisovallesiachotamine ( 3 ), 10-hydroxyisositsirikine ( 4 ), 10,11-dimethoxysitsirikine ( 5 ), 10-methoxyapoyohimbine ( 6 ), 10-hydroxyakuammidine ( 7 ), akuammidine 17- O - β - D -glucoside ( 8 ), 15 α -hydroxyapparicine ( 9 ), and 15 α -hydroxy-10-methoxyapparicine ( 10 ), and 24 known alkaloids were isolated from leaves and twigs of Ochrosia borbonica J. F. Gmel . These structures were elucidated based on 1D- and 2D-NMR, FT-IR, UV, and MS data. 10-Hydroxyisovallesiachotamine ( 3 ), ellipticine, and 10-methoxyellipticine showed cytotoxic activities against five human cancer cell lines.
Print ISSN:
0018-019X
Digitale ISSN:
1522-2675
Thema:
Chemie und Pharmazie
Permalink