Publication Date:
2012-05-17
Description:
The title compounds have been prepared from 2-bromophenyl isothiocyanates 1 . Thus, 2-lithiophenyl isothiocyanates 2 , obtained from 1 and BuLi through Br/Li exchange, reacted with Se at −78° to form lithium benzoselenazole-2-thiolates 3 , which, upon aqueous workup, afforded benzoselenazole-2(3 H )-thiones 4 . The thiolates 3 were alkylated with reactive alkyl halides and acylated with carboxylic acid chlorides to give 2-(alkylsulfanyl)benzoselenazoles 5 and S -(benzoselenazol-2-yl) thiocarboxylates 6 , respectively.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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