Publication Date:
2015-04-12
Description:
Article ATG7 promotes cardiomyocyte autophagy but the molecular mechanism of its regulation is unknown. Here, Wang et al. identify a long non-coding RNA dubbed autophagy promoting factor (APF) that binds and inhibits miR-188-3p, which in turn acts on ATG7, to regulate cardiac autophagy. Nature Communications doi: 10.1038/ncomms7779 Authors: Kun Wang, Cui-Yun Liu, Lu-Yu Zhou, Jian-Xun Wang, Man Wang, Bing Zhao, Wen-Ke Zhao, Shi-Jun Xu, Li-Hua Fan, Xiao-Jie Zhang, Chang Feng, Chao-Qun Wang, Yan-Fang Zhao, Pei-Feng Li
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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