Publication Date:
2015-05-20
Description:
Article Activation of innate immune responses is subject to versatile regulation. Here the authors show that a conserved LATS family kinase Stk38 limits proinflammatory signalling downstream of TLR9 in macrophages and protects mice from lethal sepsis by MEKK2 ubiquitination and degradation. Nature Communications doi: 10.1038/ncomms8167 Authors: Mingyue Wen, Xianwei Ma, Hong Cheng, Wei Jiang, Xiongfei Xu, Yi Zhang, Yan Zhang, Zhenhong Guo, Yizhi Yu, Hongmei Xu, Cheng Qian, Xuetao Cao, Huazhang An
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
Permalink