Publication Date:
2015-10-15
Description:
Article In Alzheimer's disease, tau spreads throughout the brain, however the nature of the tau species propagating from one neuron to another is not known. Here, Takeda et al . identify a rare, high-molecular-weight tau as the primary species taken up and transferred between synaptically connected neurons. Nature Communications doi: 10.1038/ncomms9490 Authors: Shuko Takeda, Susanne Wegmann, Hansang Cho, Sarah L. DeVos, Caitlin Commins, Allyson D. Roe, Samantha B. Nicholls, George A. Carlson, Rose Pitstick, Chloe K. Nobuhara, Isabel Costantino, Matthew P. Frosch, Daniel J. Müller, Daniel Irimia, Bradley T. Hyman
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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