Publication Date:
2015-07-30
Description:
Article Non-typeable Haemophilus influenzae , which causes ear and lung infections, has a DNA methyltransferase encoded by alternative alleles that are subject to random ON/OFF switching. Here, Atack et al. show that this epigenetic switch controls the expression of key proteins involved in virulence. Nature Communications doi: 10.1038/ncomms8828 Authors: John M. Atack, Yogitha N. Srikhanta, Kate L. Fox, Joseph A. Jurcisek, Kenneth L. Brockman, Tyson A. Clark, Matthew Boitano, Peter M. Power, Freda E.-C. Jen, Alastair G. McEwan, Sean M. Grimmond, Arnold L. Smith, Stephen J. Barenkamp, Jonas Korlach, Lauren O. Bakaletz, Michael P. Jennings
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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