Publication Date:
2015-12-05
Description:
Article Vps4 is a AAA+ family protein involved in the disassembly of ESCRT-III polymers during membrane fission events such as occur during HIV budding. Here the authors propose a structure-based model of how the conformational flexibility of Vps4 can be translated into mechanical forces to disassemble ESCRT-III during membrane fission. Nature Communications doi: 10.1038/ncomms9781 Authors: Christophe Caillat, Pauline Macheboeuf, Yuanfei Wu, Andrew A. McCarthy, Elisabetta Boeri-Erba, Gregory Effantin, Heinrich G. Göttlinger, Winfried Weissenhorn, Patricia Renesto
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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