Publication Date:
2015-04-12
Description:
Article Elastase secreted by immune cells contributes to various lung diseases; however, elastase inhibitors have mostly failed in the clinic. Here, the authors discover a second, truncated form of elastase, which is the result of autocatalytic cleavage and is not well targeted by current synthetic elastase inhibitors. Nature Communications doi: 10.1038/ncomms7722 Authors: T. Dau, R. S. J. Sarker, A. O. Yildirim, O. Eickelberg, D. E. Jenne
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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