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  • chemiluminescence  (4)
  • General Chemistry  (3)
  • Food Science, Agricultural, Medicinal and Pharmaceutical Chemistry  (1)
  • Wiley-Blackwell  (8)
  • Springer Nature
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  • Wiley-Blackwell  (8)
  • Springer Nature
  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 69 (1957), S. 422-433 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird eine Übersicht über die Struktur der wichtigsten Di- und höheren Oligo-saccharide gegeben. Ferner werden die älteren und neueren Methoden der Synthesen dieser Stoffe behandeltIn diesem Aufsatz wird die Nomenklatur, wie sie im Jahre 1952 von der American Chemical Society und der Chemical Society (London) vereinbart wurde, benützt. Diese in unserem Lande nur teilweise benützte Nomenklatur ist in der Übersetzung mit geringfügigen Änderungen beibehalten worden..
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 81 (1969), S. 933-933 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 3 (1989), S. 71-74 
    ISSN: 0884-3996
    Keywords: Monocyte ; activation ; chemiluminescence ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Human mononuclear cells were separated from freshly obtained peripheral venous blood by density centrifugation and the number of monocytes present estimated by volume spectroscopy. The mononuclear cells were then placed directly into the wells of a microtitre plate and incubated for one hour at 37°C to promote adherence of the monocytes to the plastic wells. Non-adherent cells were then removed by washing, thus avoiding the need to treat the monocytes with EDTA or other reagents during cell preparation. The time course and dynamics of the chemiluminescence response of adherent monocytes towards opsonized zymosan was similar to those seen using non-adherent cells.The ability of adherent monocyte preparations to produce chemiluminescence following incubation for varying periods with T-lymphocyte conditioned medium was investigated. The use of a microtitre plate chemiluminescence reader allows several plates to be assayed over the 24-hour period and since small numbers of cells are required, many cultures can be analysed in one experiment. This technique (Patent applied for) promises to be a powerful tool for dissecting the cellular events which occur during macrophage activation and examining the effect of various lymphokines on the ability of monocytes to produce a chemiluminescence response.
    Additional Material: 2 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 8 (1993), S. 247-252 
    ISSN: 0884-3996
    Keywords: Salmeterol ; beta-adrenergic agonist ; chemiluminescence ; lucigenin ; neutrophil ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Although beta-agonists remain an important aspect of the treatment of asthma, their role has recently been questioned. Salmeterol has recently been developed as a betaagonist with prolonged bronchodilator action. Using lucigenin-enhanced chemiluminescence, we have shown that salmeterol inhibits this aspect of phagocyte function in vitro in a concentration-dependent manner. However, salmeterol differs from classical beta2-agonists in that at concentrations between 10-5 and 10-3 mol/L, its effects on phagocytes cannot be completely reversed by washing the cells or by propanolol. The effects on phagocytes may not therefore be explicable on the basis of betaadrenergic mechanisms alone.
    Additional Material: 3 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 3 (1989), S. 67-70 
    ISSN: 0884-3996
    Keywords: Phagcyte ; mycobacteria ; chemiluminescence ; opsonization ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: The use of chemiluminescence techniques to study the interaction between bacteria and phagocytes has been useful for examining the extent to which serum factors, such as opsonins, are important in internalization of the organisms and the response of the cell to phagocytosed bacteria. However, such methods have been limited by the number of experiments which can be performed at one time using most commercial luminometers. However, the recent introduction of the Amerlite microtitre plate luminometer allows the measurement of chemiluminescence responses in 96-well microtitre plates. Using this instrument, lucigenin-enhanced chemiluminescence can be detected from as few as 5000 cells (polymorphonuclear leukocytes or monocytes) per well with a 1:10 ratio of cells to zymosan particles opsonized with 10% serum. The opsonic capacity of up to 100 sera can be measured in triplicate wells in a single experiment using four microtitre plates and polymorphonuclear leukocytes prepared from less than 40 ml freshly obtained venous blood. We are currently using this technique to investigate the effect of serum opsonins on the interaction between normal human polymorphonuclear leukocytes and monocytes with mycobacteria of three species (Mycobacterium leprae, M. tuberculosis, and M. aviumintracellulare). Other possible applications of this method are discussed.
    Additional Material: 3 Ill.
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 81 (1969), S. 933-933 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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  • 7
    ISSN: 0263-6484
    Keywords: Macrophages ; monocytes ; radical oxidation ; pteridines ; tetrahydrobiopterin ; dihydrobiopterin ; dihydroneopterin ; chemiluminescence ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Luminol-dependent chemiluminescence of normal human monocytes activated by zymosan is demonstrated to be inhibited by tetrahydrobiopterin in a concentration-dependent manner. The reduced pterins tetrahydrobiopterin, dihydrobiopterin, and dihydroneopterin are all shown to be readily oxidized by the hydroxyl radical.The susceptibility of reduced pterins to free radical attack may explain the inhibition of chemiluminescence observed and an additional role of reduced pterins as free radical scavengers in tissues is considered.
    Additional Material: 2 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Archives of Insect Biochemistry and Physiology 12 (1989), S. 231-252 
    ISSN: 0739-4462
    Keywords: sterols ; acylglycerides ; glycerol ; hemolymph ; corn earworm ; Chemistry ; Food Science, Agricultural, Medicinal and Pharmaceutical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Two vertebrate hypolipidemic agents, cholestyramine and niacin, affected the growth and development of Heliothis zea as well as the quantity of acylglyceride or sterol present in the larva. As the concentration of cholestyramine in the diet increased to 6.0%: the number of larval molts increased from 5 or 6 to as many as 7 or 8, the time required for the onset of pupation increased from 11 or 12 to 20 days, and the number of adults that emerged decreased from at least 70 to 0%. The growth and development of the insect may have slowed, at least in part, because this agent reduced the quantity of sterol and glyceride in the tissues of the larva. Niacin also affected the growth and development of the insect. As the concentration of niacin in the diet increased to 5.0%: the number of larval molts increased by 1, the time required for the onset of pupation increased to 21 days, pupal weight decreased significantly, but adult emergence was normal. The growth and development of the insect may have slowed, at least in part, because this agent caused sterol to accumulate in the hemolymph of the larva. A water-soluble component in the hemolymph also increased in the presence of niacin, but there was little or no change in the glyceride content. Further studies are warranted to determine the mode of action of these hypolipidemic agents in H. zea.
    Additional Material: 3 Ill.
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