Publication Date:
2015-04-01
Description:
Article Skp2 forms part of the SCF complex—an E3 ubiquitin ligase. Here the authors identify macroH2A1 as a novel target of Skp2 and propose an axis of regulation involving Skp2-macroH2A1-CDK8-p27 in cancer. Nature Communications doi: 10.1038/ncomms7641 Authors: Dazhi Xu, Chien-Feng Li, Xian Zhang, Zhaohui Gong, Chia-Hsin Chan, Szu-Wei Lee, Guoxiang Jin, Abdol-Hossein Rezaeian, Fei Han, Jing Wang, Wei-Lei Yang, Zi-Zhen Feng, Wei Chen, Ching-Yuan Wu, Ying-Jan Wang, Lu-Ping Chow, Xiao-Feng Zhu, Yi-Xin Zeng, Hui-Kuan Lin
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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