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  • 1
    Publikationsdatum: 2016-05-10
    Beschreibung: The role of groundwater in sustaining plant transpiration constitutes an important but not well understood aspect of the interactions between groundwater, the land surface, vegetation and the atmosphere. The effect of the hydraulic redistribution (HR) process by plant roots on the interplay between plant transpiration and groundwater dynamics under water-limited climates is investigated by using the Variable Infiltration Capacity Plus (VIC+) land surface model. Numerical experiments, with or without explicitly considering HR, are conducted on soil columns over a range of groundwater table depths (GWTDs) under different vegetative land covers, soil types and precipitation conditions. When HR is not included, this study obtains transpiration – GWTD relationships consistent with those from watershed studies that do not include HR. When HR is included, the transpiration – GWTD relationships are modified. The modification introduced by HR is manifested in the soil moisture of the root zone. The mechanism of HR is explained by detailing the roles of the hydraulically redistributed water, the upward diffusion of soil water and the daytime root uptake. We have found that HR is particularly important in water-limited climates under which plants have high transpiration demand. At the beginning stage of a dry period, HR modulates the severe impacts that climate has on plant transpiration. Only after a prolonged dry period, impacts of HR are lessened when the groundwater table drops below the depth of water uptake by roots and are diminished when plant transpiration is decoupled from groundwater dynamics. This article is protected by copyright. All rights reserved.
    Print ISSN: 0043-1397
    Digitale ISSN: 1944-7973
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 2016-06-09
    Beschreibung: ABSTRACT Bisphenol A (BPA) is an important industrial chemical, mainly used in the manufacture of polycarbonate plastic and epoxy resins. Due to its widespread use, humans have a high risk of exposure to BPA. BPA has been found to have adverse health effects such as interfering with hormone-related pathways and is well-known to act as an endocrine disruptor. The present study is the first to show the induction effect of BPA on gene expression and enzyme activity of CYP2C9 , an important hepatic drug metabolizing enzyme in human. We further identify the mechanism of BPA upregulation of CYP2C9 expression. We show that BPA is able to transcriptionally activate CYP2C9 promoter through ERα and ERE site within the CYP2C9 promoter region in HepG2 cells, and can induce CYP2C9 gene expression and enzyme activity in human primary hepatocytes. Moreover, we demonstrate that Med25, a variable member of the Mediator complex, is a coactivator of ligand-activated ERα that interacts with ERα through its C-terminal L XX LL motif after BPA exposure, and is functionally involved in BPA-induced transcriptional regulation of CYP2C9 expression and enzyme activity. Our findings suggest that BPA exposure has a potential risk for adverse health effects in human liver metabolism by upregulation of CYP2C9 expression. © 2016 Wiley Periodicals, Inc. Environ Toxicol, 2016.
    Print ISSN: 1520-4081
    Digitale ISSN: 1522-7278
    Thema: Energietechnik
    Publiziert von Wiley
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Publikationsdatum: 2016-06-10
    Beschreibung: A series of quaternary nitride solid solutions with a general formula of Sr 1− x Ca x LiAl 3 N 4 :0.5%Eu 2+ was synthesized by a solid-state reaction method. The experimental results showed that a proper amount of Ca-doping can improve the crystallinity and the photoluminescence properties of the produced phosphors. Rietveld refinement showed that the volume of the unit cell shrank with the increase of Ca substitution for Sr, which resulted in a red shift of the emission spectra from 654 to 665 nm under blue excitation at 475 nm. Rietveld refinement and CASTPE calculations suggested that Ca 2+ ions prefer to occupy the smaller Sr(I) sites in the crystal lattice, which increases the amount of Eu 2+ ions in Sr(II) sites and enables the tuning of the chromaticity coordinates of the obtained phosphors. The thermal stability of the produced phosphors is better than that of commercial Sr 2 Si 5 N 8 :Eu 2+ phosphor. The experimental results qualify the solid-solution Sr 1− x Ca x LiAl 3 N 4 :0.5%Eu 2+ for consideration as a potential candidate for application in white LEDs.
    Print ISSN: 0002-7820
    Digitale ISSN: 1551-2916
    Thema: Maschinenbau
    Publiziert von Wiley
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Publikationsdatum: 2012-08-31
    Beschreibung: A new multiscale routing framework is developed and coupled with the Hydrologically based Three-layer Variable Infiltration Capacity (VIC-3L) land surface model (LSM). This new routing framework has a characteristic of reducing impacts of different scales (both in space and time) on the routing results. The new routing framework has been applied to three different river basins with six different spatial resolutions and two different temporal resolutions. Their results have also been compared to the D8-based (eight direction based) routing scheme, whose flow network is generated from the widely used eight direction (D8) method, to evaluate the new framework's capability of reducing the impacts of spatial and temporal resolutions on the routing results. Results from the new routing framework show that they are significantly less affected by the spatial resolutions than those from the D8-based routing scheme. Comparing the results at the basins' outlets to those obtained from the instantaneous unit hydrograph (IUH) method which has, in principle, the least spatial resolution impacts on the routing results, the new routing framework provides results similar to those by the IUH method. However, the new routing framework has an advantage over the IUH method of providing routing information within the interior locations of a basin and along the river channels, while the IUH method cannot. The new routing framework also reduces impacts of different temporal resolutions on the routing results. The problem of spiky hydrographs caused by a typical routing method, due to the impacts of different temporal resolutions, can be significantly reduced.
    Print ISSN: 0043-1397
    Digitale ISSN: 1944-7973
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Publikationsdatum: 2013-10-23
    Beschreibung: The Three-Layer Variable Infiltration Capacity (VIC-3L) land surface model is extended to include biological and hydrological processes important to water, energy, and carbon budgets under water-limited climatic conditions: (1) movement of soil water from wet to dry regions through hydraulic redistribution (HR); (2) groundwater dynamics; (3) plant water storage; and (4) photosynthetic process. HR is represented with a process-based scheme and the interaction between HR and groundwater dynamics is explicitly considered. The impact of frozen soil on HR in the cold season is also represented. Transpiration is calculated by combining an Ohm's law analogy, where flow from the soil to leaves is buffered by plant water storage, with the Penman-Monteith method, where stomatal conductance is linked with photosynthesis. In this extended model (referred to as VIC+), water flow in plants and in the unsaturated and saturated zones, transpiration and photosynthesis are closely coupled, and multiple constraints are simultaneously applied to the transpiration process. VIC+ is evaluated with an analytical solution under simple conditions and with observed data at two AmeriFlux sites. Scenario simulations demonstrate the following results: (1) HR has significant impacts on water, energy and carbon budgets during the dry season; (2) Rise of groundwater table, increase of root depth, HR, and plant water storage are favorable to dry-season latent heat flux; (3) Plant water storage can weaken the intensity of upward HR; (4) Frozen soil can restrict downward HR in the wet winter and reduce the soil water reserves for the dry season.
    Print ISSN: 0043-1397
    Digitale ISSN: 1944-7973
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Publikationsdatum: 2014-09-24
    Beschreibung: A new effective parameter estimation approach is presented for the Multiscale Kalman Smoother (MKS) algorithm. As demonstrated, it shows promising potentials in deriving better data products involving sources from different spatial scales and precisions. The proposed approach employs a multi-objective parameter estimation framework, which includes three multi-objective estimation schemes (MO schemes), rather than using the conventional maximum likelihood scheme (ML scheme), to estimate the MKS parameters. Unlike the ML scheme, the MO schemes are not built on strict statistical assumptions related to prediction errors and observation errors, rather, they directly associate the fused data of multiple scales with multiple objective functions. In the MO schemes, objective functions are defined to facilitate consistency among the fused data at multiple scales and the input data at their original scales as well in terms of spatial patterns and magnitudes. Merits of the new approach are evaluated through a Monte Carlo experiment and a series of comparison analyses using synthetic precipitation data that contain noises which follow either the multiplicative error model or the additive error model. Our results show that the MKS fused precipitation performs better using the MO framework. Improvements are particularly significant for the fused precipitation associated with fine spatial resolutions. This is due mainly to the adoption of more criteria and constraints in the MO framework. The weakness of the original ML scheme, arising from its blindly putting more weights into the data associated with finer resolutions, is circumvented in the proposed new MO framework.
    Print ISSN: 0043-1397
    Digitale ISSN: 1944-7973
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Publikationsdatum: 2015-03-12
    Beschreibung: Persistent currents (PCs), one of the most intriguing manifestations of the Aharonov-Bohm (AB) effect, are known to vanish for Schrödinger particles in the presence of random scatterings, e.g., due to classical chaos. But would this still be the case for Dirac fermions? Addressing this question is of significant value due to the tremendous recent interest in two-dimensional Dirac materials. We investigate relativistic quantum AB rings threaded by a magnetic flux and find that PCs are extremely robust. Even for highly asymmetric rings that host fully developed classical chaos, the amplitudes of PCs are of the same order of magnitude as those for integrable rings, henceforth the term superpersistent currents (SPCs). A striking finding is that the SPCs can be attributed to a robust type of relativistic quantum states, i.e., Dirac whispering gallery modes (WGMs) that carry large angular momenta and travel along the boundaries. We propose an experimental scheme using topological insulators to observe and characterize Dirac WGMs and SPCs, and speculate that these features can potentially be the base for a new class of relativistic qubit systems. Our discovery of WGMs in relativistic quantum systems is remarkable because, although WGMs are common in photonic systems, they are relatively rare in electronic systems. Scientific Reports 5 doi: 10.1038/srep08963
    Digitale ISSN: 2045-2322
    Thema: Allgemeine Naturwissenschaft
    Publiziert von Springer Nature
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Publikationsdatum: 2011-08-30
    Beschreibung: With advancements in measuring techniques and modeling approaches, more and more precipitation data products, with different spatial resolutions and accuracies, become available. Therefore, there is an increasing need to produce a fused precipitation product that can take advantage of the strengths of each individual precipitation data product. This study systematically and quantitatively evaluates the improvements of the fused precipitation data as a result of using the Mulitscale Kalman Smoother-based (i.e., MKS-based) framework. Impacts of two types of errors, i.e., white noise and bias that are associated with individual precipitation products, are investigated through hypothetical experiments. Two measures, correlation and root-mean-square error, are used to evaluate the improvements of the fused precipitation data. Our study shows that the MKS-based framework can significantly recover the loss of precipitation's spatial patterns and magnitudes that are associated with the white noise and bias when the erroneous data at different spatial scales are fused together. Although the erroneous data at a finer resolution are generally more effective in improving the spatial patterns and magnitudes of the erroneous data at a coarser resolution, data at a coarser resolution can also provide valuable information in improving the quality of the data at a finer resolution when they are fused. This study provides insights on the values of the MKS-based framework and a guideline for determining a potentially optimal spatial scale over which improvements in both the spatial patterns and the magnitudes can be maximized based on given data with different spatial resolutions.
    Print ISSN: 0043-1397
    Digitale ISSN: 1944-7973
    Thema: Architektur, Bauingenieurwesen, Vermessung , Geographie
    Publiziert von Wiley im Namen von American Geophysical Union (AGU).
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Publikationsdatum: 2019
    Digitale ISSN: 2041-4889
    Thema: Biologie , Medizin
    Publiziert von Springer Nature
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 2017-06-02
    Beschreibung: RGD-modified oncolytic adenovirus-harboring shPKM2 exhibits a potent cytotoxic effect in pancreatic cancer via autophagy inhibition and apoptosis promotion Cell Death and Disease 8, e2835 (June 2017). doi:10.1038/cddis.2017.230 Authors: Yanni Xu, Liang Chu, Sujing Yuan, Yuanqin Yang, Yu Yang, Bin Xu, Kangjian Zhang, Xin-Yuan Liu, Ruwei Wang, Ling Fang, Zhinan Chen & Zongsuo Liang
    Digitale ISSN: 2041-4889
    Thema: Biologie , Medizin
    Publiziert von Springer Nature
    Standort Signatur Erwartet Verfügbarkeit
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