ISSN:
1432-0983
Keywords:
S. cerevisiae
;
Cell cycle
;
Suppression
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary A cell cycle (cdc) mutant of Saccharomyces cerevisiae is described which fails to complement cdc27-1 described by Hartwell et al. 1973), and is designated cdc27–47. Whereas cdc27-1 behaves as a single Mendelian gene (Hartwell et al. 1973), cdc27–47 requires the presence of an additional unlinked gene for expression of temperature-sensitivity. This gene, designated sts47, is present in some, but not all, laboratory wild-type strains. Expression of cdc27-1 is not influenced by STS47. A model for suppression is proposed involving the modification of conformation within a structural or enzyme complex.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00435218
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