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  • 1
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Eight pyrrolizidine alkaloids of hepatotoxic type have been indentified in leaves ofSymphytum × uplandicum The combined alkaloids exhibit chronic hepatotoxicity in rats.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Numerische Mathematik 43 (1984), S. 83-90 
    ISSN: 0945-3245
    Keywords: AMS(MOS): 65F05 ; CR: 5.14
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary A new Givens ordering is shown, empirically and by an approximate theoretical analysis, to take appreciably fewer stages than the standard scheme. Sharper error bounds than Gentleman's ensue, and the scheme is better suited to parallel computation. Other schemes, less efficient but more easily analysed, are discussed. The effect of a possible limit in practice on the number of simultaneous computations is considered.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 96 (1987), S. 1-10 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cephalopod beaks from the stomach contents of “wandering albatross” (Diomedea exulans L.) chicks from Bird Island, South Georgia, were sampled between May and September in 1983 and 1984. Lower beaks were identified and measured, and allometric data were used to calculated mantle length and biomass of the species consumed. A total of 3421 lower beaks were examined, representing 35 species in the 1983 sample and 45 species in the 1984 sample. Eight of the twenty families contributed over 95% of the biomass. In 1984 there were less Onychoteuthidae and more Ommastrephidae than in 1983 and a decrease in the number of species known to occur south of the Antarctic Polar Front. There was a difference in the size-frequency distribution of the cephalopod diet in the two years; in 1984 there was a higher frequency of intermediate-sized specimens, reflecting the greater importance of ommastrephids, especially Illex sp. The energy content of cephalopods in 1984 may have been greater than in 1983. Serial sampling of cephalopod beaks during the austral winter did not reveal evidence of growth. By the age of 200 d, wandering albatross chicks have consumed a total of approximately 100 kg wet weight of cephalopods each.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Nutrient cycling in agroecosystems 36 (1993), S. 141-150 
    ISSN: 1573-0867
    Keywords: ‘slow release’ sources ; leaching ; dry matter ; rock phosphates ; phosphorus leaching ; agronomic effectiveness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Superphosphate applied to annual pastures growing on the acidic, sandy-surfaced soils of the coastal plain areas of south-western Australia is the major cause of eutrophication of waterbodies. Watersoluble phosphate, both from freshly applied and previously applied fertilizer, is leached from the profile from deep sandy soils or moved by lateral water flow on shallow sands. As part of an integrated catchment management program for the eutrophic waterbodies, an intensive research program was conducted to develop alternatives to highly water soluble phosphatic fertilizers which were argonomically and economically effective. Field, glasshouse and laboratory work identified several sources of phosphate with low initial water solubility which were at least as effective as superphosphate, and which could be formulated and commercially produced as a practical alternative to superphosphate. On the deep sandy soils, these ‘slow release’ sources - the most useful of which was found to be sulphurfortified, partially-acidulated rock phosphates - had lower phosphorus leaching losses associated with their use than superphosphate on the basis of equal production of dry matter. The experimental work also investigated some of the factors controlling the agronomic effectiveness of these fertilizers, to enable identification of specific soils on which they are likely to be effective substitutes for superphosphate.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Nutrient cycling in agroecosystems 41 (1995), S. 129-143 
    ISSN: 1573-0867
    Keywords: fertilizer effectiveness ; relative effectiveness ; residual value ; Trifolium subterraneum ; Ornithopus compressus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The effectiveness of ‘coastal superphosphate’ and two rock phosphate fertilizers was compared with the effectiveness of single superphosphate for pasture production on deep, humic, sandy podzols in high rainfall (〉 800 mm annual average) areas of south-western Australia. The pastures were subterranean clover (Trifolium subterraneum) or mixed subterraneum clover and serradella (Ornithopus compressus). ‘Coastal superphosphate’ was made by adding rock phosphate and elemental sulphur to superphosphate during manufacture, as it came out of the den before granulation. One rock phosphate was a 50% mixture of apatite rock phosphate from Nauru and Christmas Islands, and which was also used to make the single and ‘coastal’ superphosphate used in this study, and superphosphate made in Western Australia at the time these experiments started. The other rock phosphate was Calciphos, the fertilizer produced by heating (calcining), at about 500 °C, Christmas Island C-grade ore, a calcium iron aluminium rock phosphate. There were two types of experiments. In the three Type 1 experiments, levels of each fertilizer were applied annually. In the two Type 2 experiments, levels of fertilizer were applied once only to new plots in different years. ‘Coastal superphosphate’ was the most effective fertilizer in the Type 1 experiments, with both rock phosphates and single superphosphate being equally effective. All fertilizers were equally effective in the Type 2 experiments. There were large variations in fertiliser effectiveness values between yield measurements in the same or different years. It is known that P leaches from freshly-applied superphosphate in these soils. The extent of this leaching probably varies between yield measurements affecting effectiveness values determined for all fertilizers because the effectiveness values were calculated relative to the effectiveness of single superphosphate. The humic, sandy podzols remain wet during the growing season, are acidic, and are known from laboratory studies to possess adequate hydrogen ions to cause extensive dissolution of North Carolina rock phosphate so that rock phosphates are equally or more effective than single superphosphate in these soils. When elemental sulphur in ‘coastal superphosphate’ is oxidized to SO4 hydrogen ions are produced which in previous studies has been shown to enhance dissolution of rock phosphate in ‘biosuper’, a mixture of rock phosphate and elemental sulphur.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Nutrient cycling in agroecosystems 40 (1995), S. 49-61 
    ISSN: 1573-0867
    Keywords: coastal superphosphate ; fertilizer residues ; freshly-applied fertilizer ; partially acidulated rock phosphate ; relative effectiveness ; residual value ; single superphosphate ; sodium bicarbonate ; soil test P ; Trifolium subterraneum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract “Coastal superphosphate”, a partially acidulated rock phosphate (PARP), is being considered as an alternative fertilizer to single superphosphate for pastures in high rainfall (〉 800 mm annual average) areas of south-western Australia. The effectiveness of single and coastal superphosphate, as P fertilizers, was measured in two field experiments using dry herbage yield of subterranean clover (Trifolium subterraneum). The experiments were started in April 1990 and were terminated at the end of 1993. In the years after P applications, soil samples were collected each January to measure Colwell soil-test P, which was related to plant yields measured later on that year, to provide soil P test calibrations. Relative to freshly-applied single superphosphate, the effectiveness of freshly-applied coastal superphosphate and the residues of previously-applied single and coastal superphosphate were less effective in some years (from 3% as effective to equally effective), and up to 100% more effective in other years. This large range in effectiveness values in different years is attributed to different climatic conditions. Soil P test calibrations were different for soils treated with single or coastal superphosphate. The calibrations were also different for different yield assessments (harvests) in the same year, and in different years. Consequently soil P testing can only provide a very crude estimate of the current P status of the soils.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Nutrient cycling in agroecosystems 44 (1995), S. 177-188 
    ISSN: 1573-0867
    Keywords: apatite rock phosphate ; Calciphos ; coastal superphosphate ; Colwell soil test phosphorus ; extractability ; single superphosphate ; sodium bicarbonate ; soil phosphorus test calibration ; Trifolium subterraneum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The relationships between (i) soil test phosphorus (P) (Colwell sodium bicarbonate procedure) and the level of P applied (from 0 to 1000 kg total P ha−1) (relationship 1), and (ii) yield and soil-test P (relationship 2, the soil P test calibration), were measured in two field experiments on very sandy, P-leaching soils in the high rainfall (〉 800 mm annual average) areas of south-western Australia. The soils were humic sandy podzols, or haplohumods, comprising 97% sand (20 to 2000 μm). The experiments started in April 1984 and were terminated at the end of 1990. Soil-test P, measured on soil samples collected to 5, 10 and 25 cm depth each January in the years after P application, was related to yields of dried clover (Trifolium subterraneum) herbage measured later in each year. The four P fertilizers studied were single superphosphate, coastal superphosphate (made by adding, just before granulation, extra rock phosphate together with elemental sulphur while manufacturing single superphosphate), apatite rock phosphate, and Calciphos. Relationship (1) was adequately described by a linear equation (R2 〉 0.80, most being 〉 0.90). The slope coefficient estimates the extractability of P from the soil by the Colwell procedure, and is called extractability. Relationship (2) was adequately described by the Mitscherlich equation (R2 〉 0.75, most being 〉 0.90). For relationship (2), use of percentage of the maximum (relative) yield eliminated differences due to different maximum yields and yield responses (maximum yield minus the yield for the nil-P treatment). Soil test P ranged from about 4 to 150 μg Pg−1 soil. Soil test P and extractability were generally higher for samples of the top 5 cm of the soil than the top 25 cm, and were largest for single superphosphate and lowest for apatite rock phosphate. Both extractability (relationship (1)) and the curvature coefficient of the Mitscherlich equation (relationship (2)), differed for different P fertilizers and different soil sample depths. The curvature coefficient also differed for different yield assessments (harvests) in the same or different years. Different soil P test calibrations were required for different P fertilizers, soil sample depths and harvest in the same or different years. It is concluded that soil P testing provides a crude estimate of the current P status of P-leaching soils in Western Australia.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 51 (1995), S. 1124-1134 
    ISSN: 1420-9071
    Keywords: Cell density ; density sensing ; discoidin ; prestarvation response ; starvation ; tissue size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Throughout growth and development,Dictyostelium cells secrete autocrine factors that accumulate in proportion to cell density. At sufficient concentration, these factors cause changes in gene expression. VegetativeDictyostelium cells continuously secrete prestarvation factor (PSF). The bacteria upon which the cells feed inhibit their response to PSF, allowing the cells to monitor their own density in relation to that of their food supply. At high PSF/bacteria ratios, which occur during late exponential growth, PSF induces the expression of several genes whose products are needed for cell aggregation. When the food supply has been depleted, PSF production declines, and a second density-sensing pathway is activated. Starving cells secrete conditioned medium factor (CMF), a glycoprotein of Mr 80 kDa that is essential for the development of differentiated cell types. Antisense mutagenesis has shown that cells lacking CMF cannot aggregate, and preliminary data suggest that CMF regulates cAMP signal transduction. Calculations indicate that a mechanism of simultaneously secreting and recognizing a signal molecule, as used byDictyostelium to monitor cell density, could also be used to determine the total number of cells in a tissue.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 43 (1992), S. 35-38 
    ISSN: 1432-1041
    Keywords: Theophylline ; Verapamil ; drug interaction ; healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Results of previous studies suggest that the theophylline-verapamil drug interaction may be dependent on verapamil dose. Therefore, in a randomized four-way cross over study, 12 healthy males received theophylline, as a single intravenous dose of aminophylline, alone (phase I) and after a four day regimen of oral verapamil 40 mg (phase II), 80 mg (phase III), and 120 mg (phase IV) every 8 h. Serial blood samples were collected over a 24 hour period for determination of serum theophylline concentration and subsequent pharmacokinetic analysis. Mean theophylline AUC for phase I–IV was 93.6, 105.6, 110.8, 120.1 mg · h · l−1, respectively. Mean theophylline clearance for phase I–IV was 3.89, 3.59, 3.35, and 3.20 l · h−1, respectively. The changes in AUC, clearance, andλ z were linearly correlated to verapamil dose. These results suggest that the inhibitory effect of verapamil on the pharmacokinetic disposition of theophylline is directly related to verapamil dose.
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  • 10
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Horizontal starch gel electrophoresis was used to investigate levels of genetic differentiation between four samples of the nominate squid species Martialia hyadesi Rochbrune and Mabille, 1889, obtained from regions of the Patagonian Shelf and Antarctic Polar Fron-tal Zone over 1000 km apart. M. hyadesi is an ecologically important South Atlantic ommastrephid squid and it is probable that, in the future, fishing effort will be increasingly directed towards this species. Details regarding the population structure of the species are therefore required. In comparison with the other three samples of M. hyadesi, one of the samples from the Patagonian Shelf (PAT 89II) exhibited fixed allelic differences at 16 of the 39 enzyme loci which were resolved (genetic identity, I=0.51). This high level of genetic differentiation contradicts the apparent morphological similarity between samples, indicating the presence of a cryptic or sibling congeneric species. Deviations from Hardy-Weinberg equilibrium and significant differences in allele distribution were also detected within and between the other three putative M. hyadesi samples, suggesting that the species fails to maintain effective panmixia across its geographical range. The occurrence of both temporal (1986 cf. 1989) and geographic structuring within the species complex is consequently indicated, caused possibly by an overlap of reproductively isolated stocks (stock mixing) outside their respective breeding areas. Low levels of genetic variability were detected throughout the samples examined, estimates of average heterozygosity per locus within the two species detected being in the order of 0.01 and 0.002. These values are discussed in relation to levels of genetic variability reported for other squid species, and in comparison with values typically expected for marine invertebrates.
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