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  • Hypertension  (1)
  • Key words Polyamines  (1)
  • Nicardipine  (1)
  • Springer  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Tolerance to salt stress in maize callus lines with different polyamine content (1997)
    Springer
    Plant cell reports 17 (1997), S. 119-122 
    Details
    ISSN: 1432-203X
    Keywords: Key words Polyamines ; Maize ; Callus culture ; Salt stress ; RAPD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Four callus lines from immature embryos of a self-crossed maize (Zea mays L.) hybrid cultivar were selected for “high” (two lines) and “low” (two lines) polyamine (PA) levels. Each selected line was exposed to culture media containing no (control) or 1% (0.171 m) NaCl and the relative growth rates were compared after subculture. Low-PA lines appeared to be tolerant to salt stress, while high-PA lines were sensitive. Analysis of PA at the end of the subculture showed that treated calli of sensitive lines had increased their putrescine content in comparison with their control, while putrescine remained constant in tolerant lines. Callus lines were analysed by RAPD (random amplification of polymorphic DNA) markers. One polymorphism (550-bp band) was found, demonstrating a genetic difference between the lines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002990050363
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of lipid metabolism during antihypertensive treatment with nicardipine sr (1992)
    Springer
    European journal of clinical pharmacology 43 (1992), S. 225-227 
    Details
    ISSN: 1432-1041
    Keywords: Hypertension ; Hyperlipidaemia ; Nicardipine ; lipid metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The an tihypertensive and metabolic effects of oral nicardipine SR 40 mg b. i. d. have been studied in 18 (15 m, 3 f; age 52.7 y) hypertensives with mild hypercholesterolaemia, treated for 3 months after a 2 week period on placebo. An iv Fat Tolerance Test (FTT) was also performed in 8 patients following placebo, treatment with acute nicardipine 20 mg and chronic administration of nicardipine SR. There was a significant fall in BP from 160/97 on placebo to 147/87 after 3 months on nicardipine SR with no change in heart rate. Blood lipids did not change significantly. The disappearance rate of the lipid emulsion in the ivFTT showed no significant change (K2 was 1.93% /min after placebo, 1.84 after nicardipine 20 mg and 1.71 after chronic treatment). The results suggest that nicardipine is an effective antihypertensive drug and that it is devoid of untoward effects on lipid metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02333014
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    Paper (German National Licenses)
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