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Insulin-like effect of dichloroacetic acid on hexose transport in Swiss 3T3 cells (1987)

Kitagawa, K. ; Nishino, H. ; Iwashima, A.

Springer

Cellular and molecular life sciences 43 (1987), S. 323-324

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ISSN: 1420-9071

Keywords: Hexose transport ; dichloroacetic acid ; insulin ; divalent cation ; mouse fibroblast

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Hexose transport in Swiss 3T3 cells was increased by treatment with dichloroacetic acid as well as by treatment with insulin. Neither extra-nor intracellular Ca2+ was found to be involved in their stimulatory action. On the other hand, the removal of intracellular Mg2+ resulted in a loss of the stimulation. These results suggest that dichloroacetic acid stimulates the hexose transport in Mg2+-dependent manner, similar to that of insulin.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01945569

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