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  • monooxygenase  (2)
  • Accounting  (1)
  • Springer  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of advanced manufacturing technology 8 (1993), S. 385-395 
    ISSN: 1433-3015
    Keywords: Value added ; Accounting ; CIM ; Overheads ; Concurrent engineering ; Manufacturing costs ; Investment ; Work cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Throughout manufacturing history, management has searched for tools to help it set product prices accurately. Traditionally, manufacturing managers have analysed efficiency by cost makeup with the basic elements: materials, labour, overheads. Overhead costs are allocated to units of production based on a theorical correlation with labour costs. With automation, direct labour has come to be only 1 to 20% of the total manufactured costs of products. The CIM infrastructure must incorporate a wide range of management facilities. It is now time to focus on an integrative approach which embraces design, planning, process and product costing. With the direct value approach we describe a concept which gives pertinent information to adapt strategy speedily for a better profitability. In addition an economic weighting coefficient for the analysis of job contribution in the creation of added value, it is possible to control product pricing. In this way, economic information can be an element of the product and process database and thus build up an operational decision support system by means of sharing common information.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of chemical ecology 10 (1984), S. 945-956 
    ISSN: 1573-1561
    Keywords: Cardenolide ; uscharidin ; metabolism ; monarch butterfly ; Danaus plexippus ; Lepidoptera ; Danaidae ; milkweed ; Asclepias ; N-demethylation ; mixed function oxidase ; monooxygenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Midgut and fat body homogenates of monarch butterfly larvae,Danaus plexippus L. (Lepidoptera:Danaidae), were examined for microsomal monooxygenase activity usingp-chloro-N-methylanilineN-demethylation and for the ability to metabolize a milkweed (Asclepias spp.) cardenolide (C23 steroid glycoside), uscharidin. All homogenates tested had bothN-demethylation and uscharidin biotransformation activities. Both transformations required NADPH. The monooxygenase inhibitors sesamex, SKF525A, and carbon monoxide inhibitedN-demethylation but not uscharidin biotransformation. Subsequent subcellular fractionation revealed the uscharidin biotransformation occurs in the soluble fraction and not the microsomal fraction, whileN-demethylation occurs in the microsomal fraction and not the soluble fraction. The larval NADPH-dependent microsomal monooxygenase apparently is not involved in the metabolism of uscharidin.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-1561
    Keywords: Monarch butterfly ; Asclepias spp. ; monooxygenase ; induction ; cardenolide ; aldrin epoxidation ; p-chloro-N-methylanilme demethylation ; Lepidoptera ; Danaidae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Monarch butterfly larvae were examined for NADPH-dependent monooxygenase activities. Midgut and fat body homogenates catalyzed aldrin epoxidation andp-chloro-N-methylanilineN-demethylation at consistently low rates compared to many other lepidopteran larvae. Homogenates from larvae collected from four different milkweeds (Asclepias spp.) with quite different cardenolide contents had similar levels of activity. There were no detectable variations in activity due to season or year of collection.
    Type of Medium: Electronic Resource
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