ISSN:
1573-8221
Keywords:
vascular permeability
;
microcirculation
;
stress
;
histamine
;
mast cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Immobilization of rats for 1 or 3 h leads to an increase in vascular permeability for ink particles and disturbances of the microcirculation in the mesenteric microvessels (formation of aggregates, appearance of “plasmatic vessels,” closure of arteriolar-venular shunts). An important role in the pathogeneis of these changes is played by histamine liberated from the mast cells without their undergoing degranulation. Liberation of histamine may be the trigger mechanism in the development of disturbances of vascular permeability during prolonged immobilization stress.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00802981
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