ISSN:
1573-899X
Keywords:
Rat brain slice
;
long-term potentiation
;
45Ca
;
lipid peroxidation
;
antioxidant defense
;
G-proteins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Long-term potentiation was elicited in living slices of rat olfactory cortex by stimulation of the lateral olfactory tract. A group of interdependent parameters of membrane metabolism was studied, i.e., the kinetics of45Ca metabolism, lipid peroxidation, and antioxidant defense; cytochemical measurements were made of Na+, K+-ATPase activity in neurons and glial cells; the functional (GTPase) activity of G-proteins was also studied. All parameters were compared with the bioelectrical activity of slices at three time points after tetanization, i.e., 3–5, 15, and 30 min. In most cases, regular phasic changes in metabolic parameters occurred, and their functional significance is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02462882
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