Publikationsdatum:
2014-07-20
Beschreibung:
Article Despite numerous previous studies, the nature of the interaction of transcription factors (TF) with their endogenous response elements (REs) has remained unclear. Here the authors characterize the binding of p53 and glucocorticoid receptor to their endogenous REs and find that transcriptionally productive interactions are transient and involve only a small fraction of cellular TF molecules. Nature Communications doi: 10.1038/ncomms5456 Authors: Tatsuya Morisaki, Waltraud G. Müller, Nicole Golob, Davide Mazza, James G. McNally
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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