Publication Date:
2016-09-15
Description:
Asymmetric cyanation of imines via dipeptide-derived organophosphine dual-reagent catalysis Nature Communications, Published online: 14 September 2016; doi:10.1038/ncomms12720 The Strecker reaction is a power method for the synthesis of cyano-substituted compounds. Here the authors report a dual-reagent system for asymmetric Strecker reactions, where an in situ formed organocatalyst/methyl acrylate zwitterionic adduct activates both the cyanide source and the electrophile.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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