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  • 1
    Publication Date: 2016-07-24
    Description: The Imager for Sprites and Upper Atmospheric Lightning (ISUAL) was the first specifically dedicated instrument to observe lightning-induced transient luminous events (TLE) sprites, elves, halos, and gigantic jets from space. The Imager is an intensified CCD system operating in the visible wavelength region with a filter wheel to select from 6 positions with filters. The Imager has a 5°x20° (vertical x horizontal) field of view (FOV). The Spectrophotometer (SP) is populated with 6 photometers with individual filters for emissions from the far ultra-violet to the near-infrared. An Array Photometer with two channels operating in the blue and red provides altitude profiles of the emission over 16 altitude bins each. The Associated Electronics Package (AEP) controls instrument functions and interfaces with the spacecraft. ISUAL was launched May 21, 2004 into a sun-synchronous 890 km orbit on the Formosat-2 satellite and has successfully been collecting data ever since. ISUAL is running on the night side of the orbit and is pointed to the east of the orbit down towards the limb. The instrument runs continuously and writes data to a circular buffer. Whenever the SP detects a sudden signal increase above a preset threshold, a trigger signal is generated that commands the system to keep the data for about 400 msec starting from ~50 msec before the trigger. Over its lifetime of ~11 years the system recorded thousands of TLE and also successfully observed aurora and airglow.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 2
    Publication Date: 2015-10-10
    Description: We report the blue luminous events observed by the ISUAL payload onboard the FORMOSAT-2 satellite. The ISUAL 427.8-nm-filtered Imager campaign was conducted near Australia in the summer of the Southern Hemisphere during 2008 Feb-Mar. On February 18, 2008, the 427.8-nm-filtered Imager recorded a series of blue luminous events. One blue starter and nine smaller blue starters were recorded in 2 minutes and 34 seconds in a localized region with the radius 〈 4 km over the cloud top. The average time interval between subsequent blue luminous events was ~ 17 second. The occurrence rate of blue luminous events was 3.5 events per minute, slightly lower than the occurrence rate of pixies (4.2 events per minute) but higher than the occurrence rate of gnomes and blue jets in the previous observations. The recorded first blue starter lasted up to 2–3 frame times (60–90 ms) and extended its altitude about 8 ± 0.3 km with a width of ~2-4 km over the cloud top. After the first blue starter, subsequent 9 smaller blue starters had the decreased heights of ~2-4 km, and their optical duration was shorter and is down to 1 ms. But their major emissions were 2PN 2 and 1NN 2 + , without lightning OI 777.4 nm emission. The ISUAL recorded blue smaller starters had the spatial average brightness of 130 kR for the 427.8 nm-filtered Imager with exposure time (29 ms) and 1.2 MR for the spectrophotometer (337 nm). Using the spectrophotometer, the emission time of blue starters was 1 ms. It is estimated that the 1NN 2 + emission was ~ 22 MR and the 2PN 2 emission was ~ 132 MR. We can estimate the degree of ionization was 10 −11 – 10 −12 in these blue luminous events using the 427.8nm-filtered Imager measured 1NN 2 + (0,1) emission.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 3
    Publication Date: 2016-06-25
    Description: : Branch is a web application that provides users with the ability to interact directly with large biomedical datasets. The interaction is mediated through a collaborative graphical user interface for building and evaluating decision trees. These trees can be used to compose and test sophisticated hypotheses and to develop predictive models. Decision trees are built and evaluated based on a library of imported datasets and can be stored in a collective area for sharing and re-use. Availability and implementation: Branch is hosted at http://biobranch.org/ and the open source code is available at http://bitbucket.org/sulab/biobranch/ . Contacts: asu@scripps.edu or bgood@scripps.edu Supplementary information: Supplementary data are available at Bioinformatics online.
    Print ISSN: 1367-4803
    Electronic ISSN: 1460-2059
    Topics: Biology , Computer Science , Medicine
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  • 4
    Publication Date: 2015-01-16
    Description: Given the increasing number of proteins reported to be regulated by S -nitrosylation (SNO), it is considered to act, in a manner analogous to phosphorylation, as a pleiotropic regulator that elicits dual effects to regulate diverse pathophysiological processes by altering protein function, stability, and conformation change in various cancers and human disorders. Due to its importance in regulating protein functions and cell signaling, dbSNO ( http://dbSNO.mbc.nctu.edu.tw ) is extended as a resource for exploring structural environment of SNO substrate sites and regulatory networks of S -nitrosylated proteins. An increasing interest in the structural environment of PTM substrate sites motivated us to map all manually curated SNO peptides (4165 SNO sites within 2277 proteins) to PDB protein entries by sequence identity, which provides the information of spatial amino acid composition, solvent-accessible surface area, spatially neighboring amino acids, and side chain orientation for 298 substrate cysteine residues. Additionally, the annotations of protein molecular functions, biological processes, functional domains and human diseases are integrated to explore the functional and disease associations for S -nitrosoproteome. In this update, users are allowed to search a group of interested proteins/genes and the system reconstructs the SNO regulatory network based on the information of metabolic pathways and protein-protein interactions. Most importantly, an endogenous yet pathophysiological S -nitrosoproteomic dataset from colorectal cancer patients was adopted to demonstrate that dbSNO could discover potential SNO proteins involving in the regulation of NO signaling for cancer pathways.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 5
    Publication Date: 2015-07-02
    Description: PathWhiz ( http://smpdb.ca/pathwhiz ) is a web server designed to create colourful, visually pleasing and biologically accurate pathway diagrams that are both machine-readable and interactive. As a web server, PathWhiz is accessible from almost any place and compatible with essentially any operating system. It also houses a public library of pathways and pathway components that can be easily viewed and expanded upon by its users. PathWhiz allows users to readily generate biologically complex pathways by using a specially designed drawing palette to quickly render metabolites (including automated structure generation), proteins (including quaternary structures, covalent modifications and cofactors), nucleic acids, membranes, subcellular structures, cells, tissues and organs. Both small-molecule and protein/gene pathways can be constructed by combining multiple pathway processes such as reactions, interactions, binding events and transport activities. PathWhiz's pathway replication and propagation functions allow for existing pathways to be used to create new pathways or for existing pathways to be automatically propagated across species. PathWhiz pathways can be saved in BioPAX, SBGN-ML and SBML data exchange formats, as well as PNG, PWML, HTML image map or SVG images that can be viewed offline or explored using PathWhiz's interactive viewer. PathWhiz has been used to generate over 700 pathway diagrams for a number of popular databases including HMDB, DrugBank and SMPDB.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 6
    Publication Date: 2012-07-31
    Description: A full kinetic elve model with a wide time range from microseconds to seconds and its spectral range from UV, visible to near-infrared wavelengths is developed. Not only the fast electron-impact emissions N2 1P (B3Πg - A3Σu+), N2 2P(C3Πu - B3Πg), N2 Lyman-Birge-Hopfield (a1Πg - X1Σg+), N2+ 1N (B2Σu+ - X2Σg+) and O2+ 1N (b4Σg− – a4Πu) but also the post-impulse chemiluminescenses, O2 atmospheric band (b1Σg+ – X3Σg−), O(1S – 1D) at 557.7 nm and O(1D – 3P) at 630 nm, are considered in the elve model. We calculate the dominant emissions and possible weak emissions in our elves model to analyze the relative importance of emission intensity, measured by the ISUAL imager with 5 selectable band pass filters (N21P, 762, 630, 557.7, 427.8 nm filter). The modeling emission intensities were well consistent with the measurements by Imager with different filters. This comparison could also be useful in designing the imager filters for future TLE survey missions in Earth orbit.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 7
    Publication Date: 2011-01-22
    Description: We report the 762 nm emissions in sprites recorded by the ISUAL experiment onboard the FORMOSAT-2 satellite. The 762 nm imager filter is centered at 763.3 nm with a 7 nm bandwidth at 50% transmittance. Sprite emissions in this passband include the N2 first positive (1PN2) bands, (2, 0) and (3, 1), the O2 atmospheric (atm) band (0, 0), and the hydroxyl (4, 0) emissions. Because these mixed emissions cannot be resolved in the 762 nm narrowband filter, a zero-dimensional plasma chemistry model is used to estimate the expected relative intensities of these emission bands in sprites. The computed 1PN2 brightness in a single streamer is 1.4 MR and 2.6 kR for the O2 atm band emissions at frame integration times of 30 ms. In the 762 nm passband, the 1PN2 emissions are the dominant emissions in sprites, and the ratio of 1PN2 to O2 atmospheric emissions is ∼500, while the hydroxyl emissions can be neglected. In this ISUAL 762 nm campaign, the brightest sprite out of the four recorded events has possible O2 atm band emissions that lasted more than 90 ms, and its observed brightness is consistent with the model prediction. Even though the lightning 762 nm emissions are strongly absorbed by O2 below 60 km, the ISUAL observed parent lightning emissions in this passband are still more than a factor of two brighter than those from ISUAL observed sprites. Hence for spacecraft nadir TLE detection missions, 762 nm bands may not be used as the sole signature to identify sprites, and auxiliary emission bands are needed.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 8
    Publication Date: 2011-07-30
    Description: This study presents the O I 135.6 nm airglow observation of the middle-latitude electron density enhancement during local summer nighttime by Global Ultraviolet Imager (GUVI) on board the Thermosphere Ionosphere Mesosphere Energetics and Dynamics (TIMED) spacecraft. The nighttime density enhancement at magnetic middle latitudes in the Southern Hemisphere, known as the Weddell Sea Anomaly (WSA), had been studied by using multipoint observations, and a similar anomalous nighttime enhancement was also found in the Northern Hemisphere recently. The resemblance of both anomalies at magnetic middle latitudes in the Northern and Southern Hemispheres suggests that they should be categorized as the midlatitude summer nighttime anomaly (MSNA). To further explore the three-dimensional structure of the MSNA and its day-to-day variation, the two-dimensional global radiance maps and the vertical electron density profiles derived from disk and limb scans of the TIMED/GUVI 135.6 nm airglow observations are utilized in this study. These global observations show that the northern MSNA mainly occurs in Asia, Europe, and the North Atlantic Ocean regions, while the southern MSNA occurs in the South America-Antarctica region, near the WSA region. The GUVI day-to-day observations in 2006 further illustrate that the southern MSNA appears nightly in January-February and November-December, while the northern MSNA appears in 36 out of 41 total observation nights in May-June.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 9
    Publication Date: 2012-03-21
    Description: This study revisits the sprite polarity paradox, first manifest by observations that exceptional cloud-to-ground flashes with negative polarity generally did not produce detectable sprites. The paradox is here resolved by the Transient Luminous Event (TLE) known as the halo, which on account of its inferior brightness (0.3 MR versus 1.5 MR) and substantially shorter duration (1 ms versus 10–100 ms) in comparison with the sprite, is not readily detectable in ground-based video cameras with standard field duration (16.7–20 ms). Observations with improved temporal resolution (ISUAL (Imager of Sprites and Upper Atmospheric Lightnings) from space and PIPER (Photometric Imager of Precipitated Electron Radiation) observations from the ground) provide evidence that flashes with negative polarity dominate the global halo population, and that the halo numbers are more than sufficient to account for the previously missing TLEs. The evidence for lightning polarity-dependent TLEs (sprites, positive and halos, negative) is attributable to the well established but incompletely understood contrast in the behavior of negative and positive lightning flashes to ground.
    Print ISSN: 0048-6604
    Electronic ISSN: 1944-799X
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 10
    Publication Date: 2011-07-07
    Description: On 22 July 2007, 37 blue jets/starters and 1 gigantic jet occurring over a thunderstorm in the Fujian province of China were observed from the Lulin observatory on the central mountain ridge of Taiwan. The majority of the jets were observed to occur in a 5 min window during the mature phase of the jet-producing thunderstorm. These jets have significant red band emissions. However, the blue emissions from these jets were not discernible due to severe atmospheric scattering. A model estimation of the emissions from a streamer reveals that the red emissions in blue starters and blue jets are mainly from the nitrogen first positive band (1PN2). The type II gigantic jet is the first of this type that was observed from the ground. The generation sequence of the gigantic jet begins with a blue starter, then a blue jet occurs at the same cloud top after ∼100 ms and finally develops into a gigantic jet ∼50 ms later. Using “optical strokes” as surrogates of the lightning strokes, the correlations between jets and the cloud lightning are explored. The results indicate that the occurrence of jets can be affected by the preceding local cloud-to-ground (CG) lightning or nearby lightning (intracloud (IC) or CG), while in turn the jets might also affect the ensuing lightning activity.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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