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  • 1
    Electronic Resource
    Electronic Resource
    Mutations and oncogenes : cause or effect (1984)
    [s.l.] : Nature Publishing Group
    Nature 309 (1984), S. 518-518 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR -In a field as complex as carcinogenesis, it is difficult to distinguish between cause, correlation and consequence. No thoughtful biologist needs to be reminded of the many cancer theories propounded in this century. The current version is represented by the flood of papers on oncogenes and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/309518a0
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  • 2
    Electronic Resource
    Electronic Resource
    The disparity between human cell senescence in vitro and lifelong replication in vivo (2002)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 20 (2002), S. 675-681 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Cultured human fibroblasts undergo senescence (a loss of replicative capacity) after a uniform, fixed number of ∼50 population doublings, commonly termed the Hayflick limit. It has been long known from clonal and other quantitative studies, however, that cells decline in replicative capacity ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0702-675
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  • 3
    Electronic Resource
    Electronic Resource
    Increased hyaluronic acid production on stimulation of DNA synthesis in chick embryo fibroblasts (1975)
    [s.l.] : Nature Publishing Group
    Nature 254 (1975), S. 65-66 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Chick embryo cells were cultured as described by Rein and Rubin11. They were grown at /?H 7.4 in Medium 199 with 2% tryptose phosphate broth and 1 % chicken serum. The multiplication rates of confluent cultures were controlled by manipulating pH and serum concentration of the medium9'10. Low ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/254065a0
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  • 4
    Electronic Resource
    Electronic Resource
    Magnesium required for serum-stimulation of growth in cultures of chick embryo fibroblasts (1976)
    [s.l.] : Nature Publishing Group
    Nature 263 (1976), S. 143-145 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Primary cultures of CEF were prepared as before2. Secondary cultures were plated 3?5 d before use at 10s cells per 60-mm Falcon culture dish in medium 199, containing 2% tryptose phosphate broth (TPB) and 1% chicken serum. During experimental manipulation, medium 199 containing 2% TPB was again ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/263143a0
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  • 5
    Electronic Resource
    Electronic Resource
    Differential effects of glucocorticoids on DNA synthesis in normal and virus-transformed chick embryo cells (1975)
    [s.l.] : Nature Publishing Group
    Nature 257 (1975), S. 804-806 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1 Inhibition by glucocorticoids of DNA synthesis in cultures of chick embryo cells. 106 chick embryo cells were seeded in 60-mm Petri dishes. After 3 d growth, the medium was changed to one without serum, and one of three glucocorticoids was added at the indicated concentrations for 16h. The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/257804a0
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  • 6
    Electronic Resource
    Electronic Resource
    Hinshelwood in the Pantheon? (1991)
    [s.l.] : Nature Publishing Group
    Nature 351 (1991), S. 600-600 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - James D. Watson's obituary of Luria1 was a fitting tribute to a pioneer of molecular biology. There is no doubt that the Luria-Delbriick fluctuation test played a crucial role in establishing the spontaneous nature of mutations in bacteria, and made bacteria the organisms of choice for ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/351600c0
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  • 7
    Electronic Resource
    Electronic Resource
    Molecular biology running into a cul-de-sac? (1988)
    [s.l.] : Nature Publishing Group
    Nature 335 (1988), S. 121-121 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-The answer to your question whether molecular biology is running into a dead end (Nature 335,11; 1988) is yes, if its purpose is to help understand the uniqueness of life and its functions. Your parallel with the quandaries of spectro-scopy in the 1920s before their resolution by quantum ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/335121a0
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  • 8
    Electronic Resource
    Electronic Resource
    Is HIV the causative factor in AIDS? (1988)
    [s.l.] : Nature Publishing Group
    Nature 334 (1988), S. 201-201 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-As a participant at the forum in which Peter Duesberg faced his critics (Nature 332, 574; 1988), it is my opinion that the Byzantine symptomatology of AIDS is unlikely to be simply accounted for by immunodeficiency supposedly caused by the retrovirus termed HIV. This is based on experience ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/334201a0
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