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  • Articles  (37)
  • Oxford University Press  (24)
  • Nature Publishing Group  (7)
  • Springer  (3)
  • Wiley  (3)
  • Biology  (37)
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  • Articles  (37)
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  • 1
    Electronic Resource
    Electronic Resource
    Active Penetration of Fat into Adipose Tissue (1948)
    [s.l.] : Nature Publishing Group
    Nature 161 (1948), S. 482-482 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WHEN adipose tissue of the rat, depleted of part of its fat by prolonged hunger, is incubated with blood or serum of the same rat, a decrease in the fat content of the medium can be demonstrated. Killing the tissue by heating to 80° C. abolishes this effect. The addition to the medium of sodium ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/161482a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Metabolism of 1- 14 C Lignoceric Acid in the Rat (1960)
    [s.l.] : Nature Publishing Group
    Nature 185 (1960), S. 461-462 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Lignoceric acid was isolated from peanut oil and converted to 1-14C lignoceric acid, via 1-14C tricosyl cyanide (modification of Anker's method for synthesis of myristic acid3). Contrary to the fatty acids of 18 carbon atoms or less, lignoceric acid did not form a soluble complex with serum ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/185461b0
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  • 3
    Electronic Resource
    Electronic Resource
    Intestinal Lecithinase (1957)
    [s.l.] : Nature Publishing Group
    Nature 180 (1957), S. 387-387 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It seems likely that the presence of fatty acids is obligatory for lecithinolysis. Small amounts of fatty acids (6 ^gm./ml.) were found to be present in the enzyme preparations. Lysolecithin also furnishes fatty acids due to the active lysoleeithinase present. Similarly, the activation by cephalin ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/180387a0
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  • 4
    Electronic Resource
    Electronic Resource
    Enzymic Properties of Natural Papain (1937)
    [s.l.] : Nature Publishing Group
    Nature 139 (1937), S. 249-249 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ACCORDING to the generally accepted view, papain is an enzyme which converts proteins (true ovalbumin ex-cepted) into peptones, and is without effect on the latter. Hydrolytic power towards peptones and true ovalbumin is only acquired after treatment with certain reagents (‘activators’), ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/139249a0
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  • 5
    Electronic Resource
    Electronic Resource
    Is feminine differentiation of the brain hormonally determined? (1976)
    Springer
    Cellular and molecular life sciences 32 (1976), S. 650-651 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The androgen insensitive, genetically male rat pseudohermaphrodite displays neither masculine or feminine sexual behavior when primed with the appropriate sex hormones. although in the absence of androgen imprinting the animal develops anatomically as female, our results suggest that feminine differentiation of the brain requires active imprinting by perinatal hormone(s), possibly adrenal progesterone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01990214
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  • 6
    Electronic Resource
    Electronic Resource
    Active Absorption of Glucose from the Intestine (1953)
    [s.l.] : Nature Publishing Group
    Nature 171 (1953), S. 745-746 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Though glucose disappeared from the lumen, glucose as such was not transferred across the intestinal wall, and the outer fluid showed no increased glucose content. When a similar experiment was carried out with radioactive glucose in the inner solution, a radioactive substance appeared in the outer ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/171745b0
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  • 7
    Electronic Resource
    Electronic Resource
    Acetylphosphatase in Animal Tissues (1945)
    [s.l.] : Nature Publishing Group
    Nature 156 (1945), S. 690-690 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN the course of experiments on the metabolism of acetylphosphate in rats, an enzyme which catalyses the hydrolysis of this substrate was found. The enzyme is present in homogenates as well as in cell-free extracts of liver, muscle, kidney, brain, but not in blood serum. Acetylphosphate M/20 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/156690a0
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  • 8
    Electronic Resource
    Electronic Resource
    Action of Pancreatic Extract on Fatty Liver (1937)
    [s.l.] : Nature Publishing Group
    Nature 140 (1937), S. 771-771 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Kaplan and Chaikoff1 have shown that the fatty infiltration of the liver in depancreatized insulin-treated dogs can be inhibited by the addition of raw pancreas to the usual diet. Dragstedt2 and his co-workers then showed that the active factor can be extracted ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/140771a0
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  • 9
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    Genomic Data from Extinct North American Camelops Revise Camel Evolutionary History (2015)
    Oxford University Press
    Details
    Publication Date: 2015-08-20
    Description: Recent advances in paleogenomic technologies have enabled an increasingly detailed understanding of the evolutionary relationships of now-extinct mammalian taxa. However, a number of enigmatic Quaternary species have never been characterized with molecular data, often because available fossils are rare or are found in environments that are not optimal for DNA preservation. Here, we analyze paleogenomic data extracted from bones attributed to the late Pleistocene western camel, Camelops cf. hesternus, a species that was distributed across central and western North America until its extinction approximately 13,000 years ago. Despite a modal sequence length of only around 35 base pairs, we reconstructed high-coverage complete mitochondrial genomes and low-coverage partial nuclear genomes for each specimen. We find that Camelops is sister to African and Asian bactrian and dromedary camels, to the exclusion of South American camelids (llamas, guanacos, alpacas, and vicuñas). These results contradict previous morphology-based phylogenetic models for Camelops , which suggest instead a closer relationship between Camelops and the South American camelids. The molecular data imply a Late Miocene divergence of the Camelops clade from lineages that separately gave rise to the extant camels of Eurasia. Our results demonstrate the increasing capacity of modern paleogenomic methods to resolve evolutionary relationships among distantly related lineages.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
    Published by Oxford University Press
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  • 10
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    Phylogenetic Estimation of Timescales Using Ancient DNA: The Effects of Temporal Sampling Scheme and Uncertainty in Sample Ages (2013)
    Oxford University Press
    Details
    Publication Date: 2013-01-19
    Description: In recent years, ancient DNA has increasingly been used for estimating molecular timescales, particularly in studies of substitution rates and demographic histories. Molecular clocks can be calibrated using temporal information from ancient DNA sequences. This information comes from the ages of the ancient samples, which can be estimated by radiocarbon dating the source material or by dating the layers in which the material was deposited. Both methods involve sources of uncertainty. The performance of Bayesian phylogenetic inference depends on the information content of the data set, which includes variation in the DNA sequences and the structure of the sample ages. Various sources of estimation error can reduce our ability to estimate rates and timescales accurately and precisely. We investigated the impact of sample-dating uncertainties on the estimation of evolutionary timescale parameters using the software BEAST. Our analyses involved 11 published data sets and focused on estimates of substitution rate and root age. We show that, provided that samples have been accurately dated and have a broad temporal span, it might be unnecessary to account for sample-dating uncertainty in Bayesian phylogenetic analyses of ancient DNA. We also investigated the sample size and temporal span of the ancient DNA sequences needed to estimate phylogenetic timescales reliably. Our results show that the range of sample ages plays a crucial role in determining the quality of the results but that accurate and precise phylogenetic estimates of timescales can be made even with only a few ancient sequences. These findings have important practical consequences for studies of molecular rates, timescales, and population dynamics.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
    Published by Oxford University Press
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