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  • Springer  (60)
  • National Academy of Sciences  (19)
  • Oxford University Press  (8)
  • 1
    ISSN: 1420-9071
    Keywords: Juvenile hormone esterase ; juvenile hormone epoxide hydrolase ; juvenile hormone binding protein ; reversed-phase liquid chromatography assay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We studied time-dependent metabolism of (10R)-[3H] juvenile hormone (JH) III and (10R, 11S)-[3H]JH I injected intoManduca sexta larvae; the hormones are metabolized to polar metabolites, expecially the JH acid-diol, and an unknown. Products were analyzed using a reversed-phase liquid chromatography assay. (10R)-JH III is metabolized much more rapidly than (10R, 11S)-[3H]JH I, whether injected seperately or as a mixture of hormones. The unknown metabolites of JH I and JH III were identified as phosphate conjugates of JH I and JH III diol by tandem mass spectral analysis of isolated samples. The phosphate conjugate of JH I diol is the principle end product of JH I metabolism.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 46 (1959), S. 407-408 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 95 (1987), S. 611-624 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The giant kelp Macrocystis pyrifera is one of the largest and fastest growing seaweeds and is dominant over large areas of the west coast of North America. A model of its growth has been developed which describes plant biomass and production over the course of a year as a function of environmental parameters which affect the light flux. Such parameters include water clarity, spacing between plants, bottom depth, latitude, harvesting activity, and photosynthetic response (P max and I k ). Model results for a standard set of conditions (latitude 33°N, 3 m plant spacing, water absorbance of 0.115 m-1 and 12 m depth) yield a peak daily gross production of almost 6 g C m-2 d-1, peak daily net production of almost 3 g C m-2 d-1, and a peak specific growth rate of about 0.022 d-1. Annual gross production for this case is 1 567 g C m-2 yr-1; annual net production is 537 g C m-2 yr-1. These values are comparable to those from field measurements. Size and timing of biomass and production peaks are affected by changes in the parameters describing the light field, with peaks usually occurring later in the year for more adverse circumstances. Inhigher latitudes, the seasonal variation is so extreme that the plant could not last the year at 53° N in 12 m of water, although it is able to survive the year in shallower water. Harvesting has severe effects on biomass and production. Model results suggest that light limitation is a very important constraint on kelp growth that should not be overlooked. This implies that differences in parameters describing two environments must be considered when comparing results obtained at different locales.
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  • 4
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The distribution and biomass of two species of squid, the ommastrephid arrow squid Nototodarus sloanii and the onychoteuthid squid Moroteuthis ingens, were analysed off southern New Zealand. These two species are the most important and abundant species in this region of the South Pacific Ocean. Data were obtained from extensive NIWA research cruises over 10 years. There was a sharp demarcation between the distribution of the two species, with N. sloanii occurring predominantly shallower than 600 m, with the greatest biomass less than 300 m. In contrast, M. ingens had the highest biomass between 650 and 700 m and occurred down to 1400 m. The biomass of N. sloanii reached more than 3500 kg · km−2, with an average catch rate of over 186 kg · km−2. In contrast, the biomass of M. ingens was more than an order of magnitude less, with all catch weights less than 200 kg · km−2 and an average catch rate less than 17 kg · km−2. The separation of these two species appeared to be related to depth, temperature and, possibly, salinity. N. sloanii occurred predominantly in warmer, shallower subtropical waters while M. ingens occurred in deeper, cooler subantarctic and antarctic intermediate water masses. The Subtropical Front formed a major barrier between the distribution of these two squid species.
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  • 5
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Beak length analysis was undertaken for the arrow squid Nototodarus sloanii in the New Zealand sector of the Southern Ocean between Stewart Island and the Auckland Islands. N. sloanii has a restricted range and is endemic to the waters around New Zealand and its associated southern islands, where it supports a fishery and is preyed upon by a number of fishes, marine mammals and birds. Lower rostral length (LRL) and upper rostral length (URL) were analysed to see how these beak measurements related to both mantle length (ML) and wet weight (W). Both lower and upper rostral lengths could be used as useful predictors of ML and W in N. sloanii, as relationships had limited scatter and high correlation coefficients. The relationships between LRL and ML, and URL and ML were only linear after regressing log-transformed values of beak length against ML. However, the relationships between LRL and W, and URL and W were linear without transforming either the x or y values. These results are different from previously published beak length analyses of Nototodarus in New Zealand waters.
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  • 6
    ISSN: 1432-1041
    Keywords: Tocainide ; Lignocaine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary To define the appropriate regime for the transition from intravenous lignocaine to oral tocainide after uncomplicated acute myocardial infarction, 43 patients received lignocaine to steady state. Each patient then received a tocainide dosage schedule. Plasma concentration of lignocaine and tocainide was measured frequently until the third peak plasma tocainide level. Tocainide 400 mg 8 hourly starting 4 h before cessation of lignocaine and tocainide 400 mg 4 hourly starting at the end of the infusion produced therapeutic plasma tocainide concentration (3.5–9 mg/l) only after the second dose. Tocainide 600 mg 12 hourly starting 6 h before cessation of lignocaine and tocainide 600 mg 6 hourly starting at the end of the infusion quickly achieved therapeutic plasma tocainide concentration which declined to give subtherapeutic first dose troughs of 2.42 mg/l (±0.28 SEM) and 2.79 mg/l (±0.27 SEM) respectively. Consistently therapeutic plasma tocainide concentrations were achieved by both of these regimes after the second dose. The short plasma halflife of lignocaine which for these regimes was 3.71 h (±0.25 SEM), resulted in subtherapeutic lignocaine concentrations before consistently therapeutic plasma tocainide concentrations had been achieved. On the basis of these results, the 600 mg 6 hourly tocainide dosage schedule was studied with cessation of lignocaine infusion either two or six h after the first tocainide dose. With the former regime only three of 5 patients had therapeutic lignocaine at the subtherapeutic tocainide trough. When lignocaine was discontinued on administration of the second tocainide dose however, therapeutic lignocaine concentration was maintained in all patients until tocainide was rising within the therapeutic range. The latter regime, which we would recommend, was not accompanied by increased side effects. Steady state tocainide was found to be present 12 h after the third tocainide dose allowing continued therapy with tocainide 600 mg 12 hourly.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 34 (1988), S. 613-618 
    ISSN: 1432-1041
    Keywords: doxazosin ; hypertension ; alpha1-adrenoceptor inhibitor ; adverse effects ; multicentre study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The antihypertensive efficacy of the new, once daily, alpha1-adrenoceptor inhibitor, doxazosin, was compared with placebo in 40 patients with mild to moderate hypertension. Following a dose titration the mean final daily doxazosin dose in 20 patients was 13.1 mg. Through-the-day blood pressure control was assessed by frequent measurements during 24 h hospitalisation in the 9 th week of double-blind treatment compared with similar measurements made during a 2 week single-blind placebo run-in. Mean reductions in standing and supine systolic and diastolic blood pressure during doxazosin treatment were statistically significantly greater than during placebo treatment at most hourly time points during the 24 h post-dose period. Twenty-four post-dose the mean falls in standing and supine diastolic blood pressure during doxazosin treatment were statistically significant when compared with placebo. Adverse effects during doxazosin treatment were generally minor and were tolerated or disappeared with continued therapy. No patients were withdrawn from the study due to adverse effects. We conclude that once daily doxazosin provides smooth and effective blood pressure control throughout a 24 h post-dose period.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Polar biology 17 (1997), S. 268-274 
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Individuals of the deepwater squid Moro- teuthis ingens were obtained from New Zealand waters at depths between 500 and 1452 m. Depth distribution suggested that there was an ontogenetic migration to deeper water by females in association with maturity. Males did not show any clear pattern in their depth distribution. Statolith increment analysis was also undertaken to obtain putative age and life span information. Based on statolith age estimates, M. ingens appears to be predominantly an annual species with the oldest individuals aged at 358 and 393 days for males and females respectively. The form of growth over the size range sampled was linear with females having a growth rate almost twice that of males. Back-calculated hatching dates revealed a peak in hatching in the austral winter between June and August. Maturation in males was more closely related to size rather than age whereas in females the pattern in ovary growth in relation to both mantle length and age was similar.
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  • 9
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Sectioned otoliths were used to estimate the age of 29 specimens of the smooth oreo (Pseudocyttus maculatus Gilchrist 1906) from the Falkland Islands region of the South Atlantic. This represents the first ageing study of this species in this region of the world. All specimens were immature (sub-adults), the largest having a maximum total length of 347 mm. Growth increments were observed in sectioned otoliths and assumed to be annual in periodicity. The maximum age estimate of individuals in this study was 20 years and the form of somatic growth was similar to previous research on this species from Australian waters. The otolith microstructure consisted of an inner, mostly opaque zone with wide increments followed by an outer, mostly translucent zone with narrower increments. It is suggested that these zones correspond to the two growth phases in the life history of this species, namely the pelagic juvenile phase (opaque zone) and the demersal sub-adult/adult phase (translucent zone).
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  • 10
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Prey species of the deepwater squid Moroteuthis ingens were examined for 37 large specimens captured in New Zealand waters. Caecum contents were predominantly less than 80% full and covered a range of digestion stages. The diet consisted of fish (at least seven species, of which four were myctophids) and squid. The most abundant prey was the myctophid Lampanyctodes hectoris, which was represented by 1323 otoliths from 22 caeca. The second most abundant prey was viperfish (Chauliodus sloani) and/or dragonfish (Stomias boa), represented by 537 otoliths from 17 caeca. Individual squid appeared to ingest surprisingly large numbers of fish (up to 100) during a single feeding period and could achieve feeding rates greater than 10% of their body weight per day. While some males appeared to ingest larger numbers of L. hectoris, females targeted significantly larger individuals of L. hectoris thereby ingesting a greater biomass of fish.
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