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  • Molecular Diversity Preservation International  (33)
  • MDPI Publishing  (2)
  • 1
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    Identifying the Planning Priorities for Green Infrastructure within Urban Environments Using Analytic Hierarchy Process (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-07-07
    Description: Urban environmental issues such as declining air quality and increasing urban heat island effects can be managed by the effective use of urban green spaces. Consequently, the importance of green infrastructure (GI) has rapidly increased over time. While the various functions of GI have been investigated in numerous studies, limited research has focused on prioritizing those factors which impact the planning and development of GI. This study used literature reviews, expert surveys, and an analytic hierarchy process methodology to identify and prioritize the critical factors influencing GI during the design and construction process to enhance the role of GI in urban areas. Experts were asked to prioritize four primary (ecological, landscape, usability, and economic factors) and 16 secondary aspects of GI design. Respondents strongly agreed on the importance of the ecological aspects of GI, while the government sector also highlighted the importance of economic concerns, such as ongoing maintenance. Results indicated that the priorities for creating GI require further analysis and mediation between stakeholders. Further empirical evidence should be accumulated regarding the functions of GI for policy implementation in design and construction.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 2
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    Sensors, Vol. 18, Pages 2086: Adaptive Noise Reduction Algorithm to Improve R Peak Detection in ECG Measured by Capacitive ECG Sensors (2018)
    MDPI Publishing
    In: Sensors
    Details
    Publication Date: 2018-06-30
    Description: Sensors, Vol. 18, Pages 2086: Adaptive Noise Reduction Algorithm to Improve R Peak Detection in ECG Measured by Capacitive ECG Sensors Sensors doi: 10.3390/s18072086 Authors: Minseok Seo Minho Choi Jun Seong Lee Sang Woo Kim Electrocardiograms (ECGs) can be conveniently obtained using capacitive ECG sensors. However, motion noise in measured ECGs can degrade R peak detection. To reduce noise, properties of reference signal and ECG measured by the sensors are analyzed and a new method of active noise cancellation (ANC) is proposed in this study. In the proposed algorithm, the original ECG signal at QRS interval is regarded as impulsive noise because the adaptive filter updates its weight as if impulsive noise is added. As the proposed algorithm does not affect impulsive noise, the original signal is not reduced during ANC. Therefore, the proposed algorithm can conserve the power of the original signal within the QRS interval and reduce only the power of noise at other intervals. The proposed algorithm was verified through comparisons with recent research using data from both indoor and outdoor experiments. The proposed algorithm will benefit a noise reduction of noisy biomedical signal measured from sensors.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI Publishing
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  • 3
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    Sensors, Vol. 17, Pages 2152: Application of Surface Protective Coating to Enhance Environment-Withstanding Property of the MEMS 2D Wind Direction and Wind Speed Sensor (2017)
    MDPI Publishing
    In: Sensors
    Details
    Publication Date: 2017-09-20
    Description: Sensors, Vol. 17, Pages 2152: Application of Surface Protective Coating to Enhance Environment-Withstanding Property of the MEMS 2D Wind Direction and Wind Speed Sensor Sensors doi: 10.3390/s17092152 Authors: Kyu-Sik Shin Dae-Sung Lee Sang-Woo Song Jae Pil Jung In this study, a microelectromechanical system (MEMS) two-dimensional (2D) wind direction and wind speed sensor consisting of a square heating source and four thermopiles was manufactured using the heat detection method. The heating source and thermopiles of the manufactured sensor must be exposed to air to detect wind speed and wind direction. Therefore, there are concerns that the sensor could be contaminated by deposition or adhesion of dust, sandy dust, snow, rain, and so forth, in the air, and that the membrane may be damaged by physical shock. Hence, there was a need to protect the heating source, thermopiles, and the membrane from environmental and physical shock. The upper protective coating to protect both the heating source and thermopiles and the lower protective coating to protect the membrane were formed by using high-molecular substances such as SU-8, Teflon and polyimide (PI). The sensor characteristics with the applied protective coatings were evaluated.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI Publishing
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  • 4
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    Assessing the Social Value of Ecosystem Services for Resilient Riparian Greenway Planning and Management in an Urban Community (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-05-07
    Description: Ecosystem services depend on the interrelation between people and the environment, and people are increasingly recognizing the social value of ecosystem services. Based on humans needs related to the values of ecosystem services, riparian greenways, properly planned and managed for resiliency, could provide great opportunities for social ecological change and transformation toward sustainability. We focus on the ecosystem service values of such greenways based on resilience in urban communities. The purpose of this study is to assess the social value of ecosystem services for resilient riparian greenway planning and management based on a survey of residents living near the Yangjaecheon riparian greenway in Gwacheon, South Korea. First, cluster analysis was performed with data from 485 completed surveys to identify different groups of respondents. Importance-performance analysis (IPA) was then applied to develop planning and management guidance for the riparian greenway based on group characteristics. Two distinct groups were identified: the Strong Social Value of Ecosystem Services group and the Neutral Social Value of Ecosystem Services group. Different distributions were found between the two groups based on gender and residency period, and significant differences were also found for age and familiarity with the riparian greenway. The results show what each group perceived to be important and how well the riparian greenway met their expectations regarding ecosystem services. These results indicate the perceived value of ecosystem services on the basis of the group characteristics, helping establish the direction for resilient riparian greenway planning and management approaches.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by Molecular Diversity Preservation International
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  • 5
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    Social Media Use and Job Performance in the Workplace: The Effects of Facebook and KakaoTalk Use on Job Performance in South Korea (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-05-15
    Description: The use of social media, such as social networking sites and instant messaging, in everyday life continues to spread, along with social media use in the workplace. This study examined how using social media like Facebook (social networking sites) and KakaoTalk (instant messaging) at work affects individual job performance. It also analyzed whether social media use has different effects on individual job performance depending on the characteristics of the given task. The results demonstrated that both Facebook and KakaoTalk had linearly positive effects on individual job performance. Moreover, task equivocality had a positive moderating effect on the relationship between KakaoTalk use and job performance. The results may have significant implications for firms reviewing their policies on employees’ social media use. Since using social media such as Facebook and KakaoTalk in the workplace improves job performance, firms may consider encouraging employees toward this practice. In particular, they may consider supporting those employees who perform tasks with high task equivocality in making use of instant messaging platforms.
    Electronic ISSN: 2071-1050
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Molecular Diversity Preservation International
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  • 6
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    Effect of Topically Applied Wikstroemia dolichantha Diels on the Development of Atopic Dermatitis-Like Skin Symptoms in Mice (2019)
    Molecular Diversity Preservation International
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    Publication Date: 2019-04-23
    Description: Plants of the genus Wikstroemia are traditionally used to treat inflammatory diseases like bronchitis and rheumatoid arthritis. In the present study, the anti-atopic effects of an EtOH extract of Wikstroemia dolichantha (WDE) on oxazolone- and DNCB (2,4-dinitrochlorobenzene)-induced dermatitis in mice were investigated. Both ears of BALB/c mice were exposed to oxazolone, and dorsal skins of SKH-1 hairless mice were sensitized with DNCB to induce acute eczematous atopic skin lesions. 1% WDE was applied daily to oxazolone- and DNCB-induced AD mice for two or three weeks, respectively. Total IL-4 and IgE concentrations in serum, transepidermal water loss (TEWL) and skin hydration were assessed. High-performance liquid chromatography/mass spectrometry (HPLC/MS) was used to determine the composition of WDE. Dermal application of 1% WDE grossly and histopathologically improved oxazolone- and DNCB-induced AD skin symptoms. Epidermal thickness and mast cell infiltration were significantly lower in animals treated with WDE than in vehicle controls. Furthermore, in addition to reducing DNCB-induced increases in serum IL-4 (interleukin 4) and IgE (immunoglobulin E) levels, WDE also decreased TEWL and increased skin hydration (indicative of improved skin barrier function). The four flavonoids taxifolin, aromadendrin, padmatin and chamaejasmine were tentatively identified in WDE by HPLC-DAD/QTOF-MS. The above results show WDE protected against oxazolone- and DNCB-induced AD in mice by down-regulating the TH2-associated cytokine IL-4 and improving skin barrier function and suggest WDE might be useful for the management of atopic dermatitis.
    Electronic ISSN: 2072-6643
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Published by Molecular Diversity Preservation International
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  • 7
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    Enzymatic Weight Update Algorithm for DNA-Based Molecular Learning (2019)
    Molecular Diversity Preservation International
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    Publication Date: 2019-04-10
    Description: Recent research in DNA nanotechnology has demonstrated that biological substrates can be used for computing at a molecular level. However, in vitro demonstrations of DNA computations use preprogrammed, rule-based methods which lack the adaptability that may be essential in developing molecular systems that function in dynamic environments. Here, we introduce an in vitro molecular algorithm that ‘learns’ molecular models from training data, opening the possibility of ‘machine learning’ in wet molecular systems. Our algorithm enables enzymatic weight update by targeting internal loop structures in DNA and ensemble learning, based on the hypernetwork model. This novel approach allows massively parallel processing of DNA with enzymes for specific structural selection for learning in an iterative manner. We also introduce an intuitive method of DNA data construction to dramatically reduce the number of unique DNA sequences needed to cover the large search space of feature sets. By combining molecular computing and machine learning the proposed algorithm makes a step closer to developing molecular computing technologies for future access to more intelligent molecular systems.
    Electronic ISSN: 1420-3049
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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  • 8
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    Analysis of Random Dynamics of Cell Segmented by a Modified Active Contour Method (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-09-28
    Description: To understand the dynamics of a living system, the analysis of particular and/or cellular dynamics has been performed based on shape-based center point detection. After collecting sequential time-lapse images of cellular dynamics, the trajectory of a moving object is determined from the set of center points of the cell analyzed from each image. The accuracy of trajectory is significant in understanding the stochastic nature of the dynamics of biological objects. In this study, to localize a cellular object in time-lapse images, three different localization methods, namely radial symmetry, circular Hough transform, and modified active contour, were considered. To analyze the accuracy of cellular dynamics, several statistical parameters such as mean square displacement and velocity autocorrelation function were employed, and localization error derived from these was reported for each localization method. In particular, through denoising using a Poisson noise filter, improved localization characteristics could be achieved. The modified active contour with denoising reduced localization error significantly, and thus allowed for accurate estimation of the statistical parameters of cellular dynamics.
    Electronic ISSN: 2076-3417
    Topics: Natural Sciences in General
    Published by Molecular Diversity Preservation International
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  • 9
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    Suppression of DNCB-Induced Atopic Skin Lesions in Mice by Wikstroemia indica Extract (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-01-08
    Description: Wikstroemia indica (L.) C.A. Mey. is used in traditional Chinese medicine to treat inflammatory diseases such as arthritis and bronchitis. In this study, we aimed to investigate the effects of an ethanolic extract of W. indica on cutaneous inflammation in mice with 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD). Dermal administration of W. indica ethanolic extract to DNCB-sensitized hairless mice with dermatitis, for two weeks, reduced erythema, scaling, and edema. Skin hydration was improved and transepidermal water loss was reduced at a W. indica concentration of 1%. Furthermore, W. indica also significantly reduced serum IgE and IL-4 concentrations in our mouse model. These results suggest that W. indica has potential as a topical treatment for AD and as an adjunctive agent to control AD.
    Electronic ISSN: 2072-6643
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Published by Molecular Diversity Preservation International
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  • 10
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    Epigenetic Modification as a Regulatory Mechanism for Spatiotemporal Dynamics of ANO1 Expression in Salivary Glands (2019)
    Molecular Diversity Preservation International
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    Publication Date: 2019-12-13
    Description: Anoctamin1 (ANO1), a calcium activated chloride channel, is known to play a critical role in salivary secretion. In the salivary gland, ANO1 is expressed exclusively in the acinar cells, with no expression in the ductal cells. However, the mechanisms that determine this distinctive cell type-dependent expression pattern of ANO1 remain unknown. In this study, we discovered that the cell-dependent expression of ANO1 during salivary gland organogenesis is regulated by DNA methylation of ANO1 CpG islands. ANO1 CpG islands in e12 embryonic submandibular glands (eSMG) are highly methylated, but those in e14 eSMG or adult SMG are significantly unmethylated. The differential expression pattern of ANO1 in duct and acini is defined at e14. Artificial demethylation by treatment with the demethylating agent 5-aza-2’-deoxycytidine (5-Aza-CdR), induced the expression of ANO1 in both the ductal cell line Human Submandibular Gland (HSG) and in the duct cells of adult mouse SMG. During the trans-differentiation in Matrigel of duct-origin HSG cells into acinar-like phenotype, significant demethylation of ANO1 CpG islands is observed. This may be due to the reduced expression of DNA methyltransferase (DNMT) 3a and 3b. These results suggest that the differential expression of ANO1 in salivary glands during organogenesis and differentiation is mainly regulated by epigenetic demethylation of the ANO1 gene.
    Print ISSN: 1661-6596
    Electronic ISSN: 1422-0067
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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