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  • Wiley  (6)
  • Molecular Diversity Preservation International  (3)
  • IOS Press  (1)
  • 1
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    Large enhancement of piezoelectric properties and resistivity in Cu/Ta co‐doped Bi4Ti3O12 high‐temperature piezoceramics (2019)
    Wiley
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    Publication Date: 2019
    Description: Abstract In this study, the electrical properties of Bi4Ti3O12‐based Aurivillius‐type ceramics were tailored by a B‐site co‐doping strategy combining high valence Ta5+ and low valence Cu2+. A series of Bi4Ti3−x(Cu1/3Ta2/3)xO12 (BTCT) (x = 0, 0.005, 0.01, 0.015, 0.02, 0.025, and 0.03) ceramics were prepared by the conventional solid‐state reaction method. The effect of Cu/Ta co‐doping on the crystal structure, microstructure, dielectric properties, piezoelectric properties, ferroelectric properties, and electrical conductivity of these ceramics was systematically investigated. Co‐doping significantly enhanced the piezoelectric properties and DC electrical resistivity of the resulting composites. The optimized comprehensive performances were obtained at x = 0.015 with a large piezoelectric coefficient (34 pC/N) and a relatively high resistivity of 9.02 × 106 Ω cm at 500°C. Furthermore, the ceramic also exhibited stable thermal annealing behaviors and excellent fatigue resistance. The results of this study demonstrated great potential of the Cu/Ta co‐doped Bi4Ti3O12 ceramics for high‐temperature piezoelectric device applications.
    Print ISSN: 0002-7820
    Electronic ISSN: 1551-2916
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
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  • 2
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    Cytotoxic Amides and Quinolones from Clausena lansium (2014)
    Wiley
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    Publication Date: 2014-02-14
    Description: Two new amides, claulansamides A and B ( 1 and 2 , resp.), together with five known amides, 3 – 7 and six known quinolones, 8 – 13 , were isolated from the stems and roots of Clausena lansium. Their structures were elucidated on the basis of extensive spectroscopic methods. Their absolute configurations were determined by single-crystal X-ray diffraction technique, CD, and optical rotation. HPLC Chiral separation of 1 afforded two enantiomers, (+)- and (−)-claulansamide A, respectively. Compounds 9, 12 , and 13 were isolated from the genus Clausena for the first time. All compounds were evaluated for their cytotoxic activities against A549, BGC-823, and HeLa cancer cell lines. However, only 9 showed cytotoxic activity against A549 cell line with an IC 50 value of 46.3 μ M , and 11 against BGC-823 and HeLa cell lines with the IC 50 values of 55.0 and 14.7 μ M , respectively.
    Print ISSN: 0018-019X
    Electronic ISSN: 1522-2675
    Topics: Chemistry and Pharmacology
    Published by Wiley
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  • 3
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    Role of oxygen‐vacancy in piezoelectric properties and fatigue behavior of (Bi0.5Na0.5)0.93Ba0.07Ti1+xO3 ceramics (2019)
    Wiley
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    Publication Date: 2019
    Description: Abstract In this reported study, (Bi0.5Na0.5)0.93Ba0.07Ti1+xO3 (abbreviated as BNBT1+x) ceramics, containing Ti‐nonstoichiometry that ranged from a 2% deficiency to a 1% excess, were designed and systematically characterized. The results of the X‐ray diffraction Rietveld refinement and X‐ray photoelectron spectroscopy analysis of these materials revealed that the amount of Ti in the BNBT1+x ceramics significantly affected the degree of coexistent rhombohedral/tetragonal phases and also affected the content of singly/doubly charged oxygen‐vacancy (Vȯ/Vö) in the ceramics. After poling and 105 fatigue cycles, the variation in Raman resonance line‐width of the Ti‐O bond in the BNBT1+x ceramics was found to be strongly dependent on the amount of Ti in the ceramic. The Ti(3+)′Ti4+–Vȯ→Ti(3+)′Ti4+–Vö transformation and clustering of the Ti(3+)′Ti4+–Vö defects under electrical loading was considered to be a critical factor in electric‐field induced structural transition and fatigue properties of the material. This article is protected by copyright. All rights reserved.
    Print ISSN: 0002-7820
    Electronic ISSN: 1551-2916
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
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  • 4
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    Calcium Uptake via Mitochondrial Uniporter Contributes to Palmitic Acid-induced Apoptosis in Mouse Podocytes (2017)
    Wiley
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    Publication Date: 2017-02-10
    Description: Podocytes are component cells of the glomerular filtration barrier, and their loss by apoptosis is the main cause of proteinuria that leads to diabetic nephropathy (DN). Therefore, insights into podocyte apoptosis mechanism would allow a better understanding of DN pathogenesis and thus help develop adequate therapeutic strategies. Here, we investigated the molecular mechanism of palmitic acid-inhibited cell death in mouse podocytes, and found that palmitic acid increased cell death in a dose- and time-dependent manner. Palmitic acid induces apoptosis in podocytes through up-regulation of cytosolic and mitochondrial Ca 2+ , mitochondrial membrane potential (MMP), cytochrome c release and depletion of endoplasmic reticulum (ER) Ca 2+ , The intracellular calcium chelator, 1,2-bis (2-aminophenoxy) ethane- N , N , N , N ′-tetraacetic acid tetrakis acetoxymethyl ester (BAPTA-AM), partially prevented this up-regulation whereas 2-aminoethoxydiphenyl borate (2-APB), an inositol 1,4,5-triphosphate receptor (IP3R) inhibitor; dantrolene, a ryanodine receptor (RyR) inhibitor; and 4,4'-diisothiocyanatostibene-2,2'-disulfonic acid (DIDS), an anion exchange inhibitor, had no effect. Interestingly, ruthenium red and Ru360, both inhibitors of the mitochondrial Ca 2+ uniporter (MCU), blocked palmitic acid-induced mitochondrial Ca 2+ elevation, cytochrome c release from mitochondria to cytosol, and apoptosis. siRNA to MCU markedly reduced curcumin-induced apoptosis. These data indicate that Ca 2+ uptake via mitochondrial uniporter contributes to palmitic acid-induced apoptosis in mouse podocytes. This article is protected by copyright. All rights reserved
    Electronic ISSN: 0091-7419
    Topics: Biology , Chemistry and Pharmacology , Medicine
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  • 5
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    Structural Features of Three Hetero-Galacturonans from Passiflora foetida Fruits and Their in Vitro Immunomodulatory Effects (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-03-08
    Description: Passiflora foetida is a horticultural plant and vital traditional Chinese herbal medicine. In our previous study, the characterization and immuno-enhancing effect of fruits polysaccharide 1 (PFP1), a water-eluted hetero-mannan from wild Passiflora foetida fruits, were investigated. Herein, another three salt-eluted novel polysaccharides, namely PFP2, PFP3, and PFP4, were obtained and structurally characterized. The results showed that PFP2, PFP3, and PFP4 were three structurally similar hetero-galacturonans with different molecular weights of 6.11 × 104, 4.37 × 104, and 3.48 × 105 g/mol, respectively. All three of these hetero-galacturonans are mainly composed of galacturonic acid, galactose, arabinose (75.69%, 80.39%, and 74.30%, respectively), and other monosaccharides including mannose, fucose, glucose, ribose, xylose, and glucuronic acid (24.31%, 19.61, and 25.70%, respectively), although differences in their backbone structure exist. Additionally, immunomodulatory assay indicated that the three hetero-galacturonans possess the ability to promote the production of nitric oxide (NO), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) in RAW264.7 macrophages in a concentration-dependent manner (p 〈 0.05). Especially, PFP3 displayed a stronger enhancing effect than PFP2 and PFP4 at the minimum effective concentration. Therefore, the results suggested that the obtained three salt-eluted hetero-galacturonans, especially PFP3, could be utilized as immunomodulatory effectivity ingredients in nutritional/pharmaceutical industries.
    Electronic ISSN: 2073-4360
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Process Engineering, Biotechnology, Nutrition Technology
    Published by Molecular Diversity Preservation International
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  • 6
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    Double Deep Q-Network with a Dual-Agent for Traffic Signal Control (2020)
    Molecular Diversity Preservation International
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    Publication Date: 2020-02-29
    Description: Adaptive traffic signal control (ATSC) based on deep reinforcement learning (DRL) has shown promising prospects to reduce traffic congestion. Most existing methods keeping traffic signal phases fixed adopt two agent actions to match a four-phase suffering unstable performance and undesirable operation in a four-phase signalized intersection. In this paper, a Double Deep Q-Network (DDQN) with a dual-agent algorithm is proposed to obtain a stable traffic signal control policy. Specifically, two agents are denoted by two different states and shift the control of green lights to make the phase sequence fixed and control process stable. State representations and reward functions are presented by improving the observability and reducing the leaning difficulty of two agents. To enhance the feasibility and reliability of two agents in the traffic control of the four-phase signalized intersection, a network structure incorporating DDQN is proposed to map states to rewards. Experiments under Simulation of Urban Mobility (SUMO) are carried out, and results show that the proposed traffic signal control algorithm is effective in improving traffic capacity.
    Electronic ISSN: 2076-3417
    Topics: Natural Sciences in General
    Published by Molecular Diversity Preservation International
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  • 7
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    A novel purification machine and fuzzy inference method based hybrid model for wind speed forecasting (2020)
    IOS Press
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    Publication Date: 2020-10-07
    Description: As one kind of readily available renewable energy sources, wind is widely used in power generation where wind speed plays an important role. Generally speaking, we need to forecast the wind speed for improving the controllability of wind power generation. However, there exists considerable randomness and instabilities in wind speed data so that it is difficult to obtain accurate forecasting results. In this paper, we propose a novel fuzzy inference method based hybrid model for accurate wind speed forecasting. In this hybrid model, we adopt two strategies to enhance the estimation performance. On one hand, we propose the purification machine which utilize the Irregular Information Reduction Module (IIRM) and the Irrelevant Variable Reduction Module (IVRM) to reduce the randomness and instabilities of the data and to eliminate the variables with zero or negative effect in the wind speed time series. On the other hand, we adopt the developed Single-Input-Rule-Modules based Fuzzy Inference System (SIRM-FIS), the functionally weighted SIRM-FIS (FWSIRM-FIS) to realize the prediction of wind speed. This FWSIRM-FIS utilizes the multi-variable functional weights to dynamically measure the importance of the input variables so that the input-output mapping can be strengthened and more accurate forecasting results can be achieved. Furthermore, detailed experiments and comparisons are given. Experimental results demonstrate that the proposed FWSIRM-FIS and purification machine contributes greatly to deal with the randomness and instability in the wind speed data and yield more accurate forecasting results than those existing excellent forecasting models.
    Print ISSN: 1064-1246
    Electronic ISSN: 1875-8967
    Topics: Mathematics
    Published by IOS Press
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  • 8
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    Test on Elastic Anisotropic Coefficients of Gas Coal (2008)
    Wiley
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    Publication Date: 2008-05-01
    Print ISSN: 0898-9591
    Electronic ISSN: 2326-0440
    Topics: Geosciences , Physics
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  • 9
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    A Comprehensive Study of Geological, Seismic and Geochemical Characteristics and Perspective Prediction for Gas Hydrate in Marine Area E (2004)
    Wiley
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    Publication Date: 2004-11-01
    Print ISSN: 0898-9591
    Electronic ISSN: 2326-0440
    Topics: Geosciences , Physics
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  • 10
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    New Polyketides from the Antarctic Fungus Pseudogymnoascus sp. HSX2#-11 (2021)
    Molecular Diversity Preservation International
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    Publication Date: 2021-03-22
    Description: The species Pseudogymnoascus is known as a psychrophilic pathogenic fungus with a ubiquitous distribution in Antarctica. Meanwhile, the study of its secondary metabolites is infrequent. Systematic research of the metabolites of the fungus Pseudogymnoascus sp. HSX2#-11, guided by the method of molecular networking, led to the isolation of one novel polyketide, pseudophenone A (1), along with six known analogs (2–7). The structure of the new compound was elucidated by extensive spectroscopic investigation and single-crystal X-ray diffraction. Pseudophenone A (1) is a dimer of diphenyl ketone and diphenyl ether, and there is only one analog of 1 to the best of our knowledge. Compounds 1 and 2 exhibited antibacterial activities against a panel of strains. This is the first time to use molecular networking to study the metabolic profiles of Antarctica fungi.
    Electronic ISSN: 1660-3397
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
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