Publication Date:
2013-01-01
Description:
In the present investigation, 1,2,4-triazole appended to pyrazoline and pyrazole rings (4a–g) using N-arylsydnone as synthon was prepared. The title compounds were subjected to Osiris property explorer for the oral bioavailability to analyze their drug likeness and drug score. Further, the compounds were subjected to the antimicrobial activity and analyzed the IC 50 and MIC values.
Print ISSN:
2090-9063
Electronic ISSN:
2090-9071
Topics:
Chemistry and Pharmacology
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