ALBERT

Description: Streptomyces are widely used for the production of secondary metabolites with diverse biological activities, including antibiotics. The necessity of alternative antimicrobial agents against multidrug-resistant pathogens is indispensable. However, the production of new therapeutics is delayed in recent days. Thus, the isolation of new Streptomyces species has drawn attention. Nepal—a country rich in biodiversity—has got high possibilities for the discovery of members of actinomycetes, especially in the higher altitudes. However, in vain, only a few screening research works have been reported from Nepal to date. Streptomyces species were isolated on ISP4 media, and characterization was performed according to morphological similarity and 16S rRNA sequence similarity using bioinformatic tools. Ethyl acetate extracts of Streptomyces species were prepared, and the antimicrobial activity was carried out using agar well diffusion technique. In this report, 18 Streptomyces species isolated from the soil were reported based on sequence analysis of 16S rRNA. Among them, 12 isolates have shown antibacterial activity against extended-spectrum beta-lactamase- (ESBL-) producing Escherichia coli. Here, we have also analyzed 16S rRNA in 27 Streptomyces species whose whole-genome sequence is available, which has revealed that some species have multiple copies of the 16S gene (∼1.5 kb) with significant variation in nucleotides. In contrast, some Streptomyces species shared identical DNA sequences in multiple copies of 16S rRNA. The sequencing of numerous copies of 16S rRNA is not necessary, and the molecular sequencing of this region is not sufficient for the identification of bacterial species. The Streptomyces species-derived ethyl acetate extracts from Nepalese soil demonstrate potential activity against ESBL-producing E. coli. Thus, they are potential candidates for antibiotics manufacturing in the future.

Description: In this work, the result of reachable set bounding and extended dissipative control synthesis of the Markovian jump time-delayed system is studied subject to stochastic actuator failures and partially known transition probabilities. Specifically, a novel actuator fault model is designed, in which the actuator fault matrix satisfies a certain probabilistic condition. Under the construction of an appropriate Lyapunov–Krasovskii functional (LKF), as well as reciprocal convex approach, Jensen’s integral inequality, and reachable set lemma, delay-dependent sufficient criteria are obtained in terms of linear matrix inequalities (LMIs) for finding an ellipsoid to bound the reachable sets of the Markovian jump time-delayed system with bounded disturbances. Finally, two numerical examples are provided to validate the effectiveness of the proposed strategy.

Description: Piezoelectric-stack actuated platforms are very popular in the parlance of nanopositioning with myriad applications like micro/nanofactory, atomic force microscopy, scanning probe microscopy, wafer design, biological cell manipulation, and so forth. Motivated by the necessity to improve trajectory tracking in such applications, this paper addresses the problem of rate dependent hysteretic nonlinearity in piezoelectric actuators (PEA). The classical second order Dahl model for hysteresis encapsulation is introduced first, followed by the identification of parameters through particle swarm optimization. A novel inversion based feedforward mechanism in combination with a feedback compensator is proposed to achieve high-precision tracking wherein the paradoxical concept of noise as a performance enhancer is introduced in the realm of PZAs. Having observed that dither induced stochastic resonance in the presence of periodic forcing reduces tracking error, dither capability is further explored in conjunction with a novel output harmonics based adaptive control scheme. The proposed adaptive controller is then augmented with an internal model control based approach to impart robustness against parametric variations and external disturbances. The proposed control law has been employed to track multifrequency signals with consistent compensation of rate dependent hysteresis of the PEA. The results indicate a greatly improved positioning accuracy along with considerable robustness achieved with the proposed integrated approach even for dual axis tracking applications.

Description: Studying the behavior of soil contaminated by diesel requires the measurement and calculation of electrical parameters such as permittivity and backscattering coefficient. It is also necessary to study the physical parameters such as surface roughness. The intent of this paper is to present a broad and updated overview of the diesel oil contaminated soil, emphasizing permittivity and scattering coefficient that are involved in determining and detecting the rate at which and extent to which hydrocarbons contaminate the soil and environment. The measurement of permittivity and the calculations of backscattering coefficient values were made with different amounts of diesel oil contamination and different incident angles in 5° intervals ranging from 10° to 80° for both horizontal and vertical polarization at C band. The values of scattering coefficient for different look angles (25°, 30°, 35°, 40°, 45°, 50°, and 55°) were calculated and are suitable for comparison with data generated from other remote sensing platforms. Accurate electrical parameter measurements of soil contamination and recognition of their dependence on physical and chemical composition are interesting and can support using microwave remote sensing instruments to observe the earth.

Description: A methodology for probabilistic modeling of fatigue damage accumulation for single stress level and multistress level loading is proposed in this paper. The methodology uses linear damage accumulation model of Palmgren-Miner, a probabilistic

Description: South Purulia Shear Zone (SPSZ) is an important area for the prospect of uranium mineralization and no detailed geophysical investigations have been carried out in this region. To delineate the subsurface structure in the present area, vertical electrical soundings using Schlumberger array and gravity survey were carried out along a profile perpendicular to the SPSZ. Apparent conductance in the subsurface revealed a possible connection from SPSZ to Raghunathpur. The gravity model reveals the presence of a northerly dipping low density zone (most likely the shear zone) extending up to Raghunathpur under a thin cover of granitic schist of Chotanagpur Granite Gneissic Complex (CGGC). The gravity model also depicts the depth of the zone of density low within this shear zone at ~400 m near Raghunathpur village and this zone truncates with a steep slope. Integration of resistivity and gravity study revealed two possible contact zones within this low density zone in the subsurface at depth of 40 m and 200 m. Our study reveals a good correlation with previous studies in Raghunathpur area characterized by medium to high hydro-uranium anomaly. Thus the conducting zone coinciding with the low gravity anomaly is inferred to be a possible uranium mineralized zone.

Description: The numerical study of the natural convection loss occurring from cylindrical solar cavity receivers is reported in this communication. These cavity receivers can be used with solar dish concentrators for process heat applications at medium temperature levels. Three cylindrical cavity receivers of diameter 0.2, 0.3, and 0.4 m with aspect ratio equal to one and opening ratios of 1 and 0.5 are used for the analysis. Fluent CFD software is used for the analysis of the three-dimensional (3D) receiver models. In this study the receiver tubes within the cylindrical cavity are modeled as a helical coil similar to those existing in actual systems. The flow of the working fluid within the helical coil is also modeled. The simulations are performed for fluid inlet temperatures of 150°C and 250°C and for receiver inclination angles of 0 (sideways-facing cavity), 30, 45, 60, and 90 degree (vertically downward-facing receiver). It is found that the convective loss increases with increasing mean fluid temperature and decreases with, increase in receiver inclination. The convective loss is found to increase with, opening ratio. These observations are true for all cavity receivers analysed here. A Nusselt number correlation involving Rayleigh numbers, receiver inclinations, and opening ratios is proposed for the convective loss.

Description: The compressed baryonic matter (CBM) experiment planned at the Facility for Antiproton and Ion Research (FAIR) will provide a major scientific effort for exploring the properties of strongly interacting matter in the high baryon density regime. One of the important goals behind such experiment is to precisely determine the equation of state (EOS) for the strongly interacting matter at extremely large baryon density. In this paper, we have used some successful models for RHIC and LHC energies to predict different particle ratios and the total multiplicity of various hadrons in the CBM energy range, that is, from 10 A GeV to 40 A GeV lab energies, which corresponds to 4.43 A GeV and 8.71 A GeV center-of-mass energies. Our main emphasis is to estimate the strange particles enhancement as well as an increase in the net baryon density at CBM experiment. We have also compared the model results with the experimental data obtained at alternating gradient synchrotron (AGS) and super proton synchrotron (SPS).

Description: The numerical study of the natural convection loss occurring from cylindrical solar cavity receivers is reported in this communication. These cavity receivers can be used with solar dish concentrators for process heat applications at medium temperature levels. Three cylindrical cavity receivers of diameter 0.2, 0.3, and 0.4 m with aspect ratio equal to one and opening ratios of 1 and 0.5 are used for the analysis. Fluent CFD software is used for the analysis of the three-dimensional (3D) receiver models. In this study the receiver tubes within the cylindrical cavity are modeled as a helical coil similar to those existing in actual systems. The flow of the working fluid within the helical coil is also modeled. The simulations are performed for fluid inlet temperatures of 150°C and 250°C and for receiver inclination angles of 0 (sideways-facing cavity), 30, 45, 60, and 90 degree (vertically downward-facing receiver). It is found that the convective loss increases with increasing mean fluid temperature and decreases with, increase in receiver inclination. The convective loss is found to increase with, opening ratio. These observations are true for all cavity receivers analysed here. A Nusselt number correlation involving Rayleigh numbers, receiver inclinations, and opening ratios is proposed for the convective loss.

Description: Here, we have used the green method for synthesis of silver and gold nanoparticles. In the present study the silver (Ag) and gold (Au) nanoparticles (NPs) were synthesized by using the aqueous bark extract of Indian spice dalchini (Cinnamomum zeylanicum) (C. zyelanicum or C. verum J. Presl). Additionally, we have used these synthesized nanoparticles for mosquito control. The larvicidal activity has been tested against the malaria vector Anopheles stephensi and filariasis vector Culex quinquefasciatus. The results were obtained using UV-visible spectrophotometer and the images were recorded with a transmission electron microscope (TEM). The efficacy tests were then performed at different concentrations and varying numbers of hours by probit analysis. The synthesized AgNPs were in spherical shape and average sizes (11.77 nm AgNPs and 46.48 nm AuNPs). The larvae of An. stephensi were found highly susceptible to the synthesized AgNPs and AuNPs than the Cx. quinquefasciatus. These results suggest that the C. zeylanicum synthesized silver and gold nanoparticles have the potential to be used as an ideal ecofriendly approach for the control of mosquito.