Publication Date:
2015-08-02
Description:
Article ER stress is associated with the pathogenesis of chronic kidney disease (CKD) and new CKD therapies are needed. Here the authors show that expression of Rtn1 can control severity of renal disease and that inhibition of its expression can attenuate ER stress and CKD. Nature Communications doi: 10.1038/ncomms8841 Authors: Ying Fan, Wenzhen Xiao, Zhengzhe Li, Xuezhu Li, Peter Y. Chuang, Belinda Jim, Weijia Zhang, Chengguo Wei, Niansong Wang, Weiping Jia, Huabao Xiong, Kyung Lee, John C. He
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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